Alayed Khalid M, AlKhawashki Ahmed M, Mokhtar Abdulmalik M, Alnafisah Raghad A, Alammari Khawla A, Alsharif Malak F
Internal Medicine, King Saud University Medical City, Riyadh, SAU.
College of Medicine, King Saud University Medical City, Riyadh, SAU.
Cureus. 2024 Oct 2;16(10):e70695. doi: 10.7759/cureus.70695. eCollection 2024 Oct.
Background and significance Bariatric surgery is an effective surgical intervention for weight loss and metabolic improvement. Articles tackling obesity and bariatric surgery with its preoperative preferences and postoperative findings are needed. From that stance, we aim to accurately document the impact of bariatric surgery, particularly laparoscopic sleeve gastrectomy (LSG), on body mass index (BMI) and glycated hemoglobin (HbA1c) levels. Patients and methods We present a retrospective cohort study conducted on 111 LSG patients from a total of 1633 patients who underwent bariatric surgery from January 23, 2018, to December 31, 2019, at King Saud University Medical City in Riyadh, Saudi Arabia. Patients were divided into three groups: nondiabetics, prediabetics, and diabetics. For each group, demographic characteristics as well as preoperative and postoperative BMI and HbA1c values were collected. Results The mean patient age was 41.35±11.8 years, with 56.8% being female. Our analysis showed that BMI values for all three groups had a significant and nearly similar overall decrease in value postoperatively (mean difference: 14.43, p<0.001). HbA1c levels also significantly improved, with the largest reduction seen in the diabetic group (from 8.7±1.5 to 6.6±1.4, p<0.001), followed by the prediabetic group (from 5.9±0.2 to 5.4±0.3, p<0.001) and the nondiabetic group (from 5.4±0.1 to 5.2±0.3, p=0.003). Conclusion LSG leads to significant improvements in BMI and HbA1c levels. Postoperatively, diabetic patients showed the greatest reduction in HbA1c percentage, supporting LSG's role in enhancing metabolic health.
背景与意义
减重手术是一种有效的手术干预方式，可用于减轻体重和改善代谢。需要有文章探讨肥胖症及减重手术，包括其术前偏好和术后结果。基于此立场，我们旨在准确记录减重手术，尤其是腹腔镜袖状胃切除术（LSG）对体重指数（BMI）和糖化血红蛋白（HbA1c）水平的影响。
患者与方法
我们对2018年1月23日至2019年12月31日在沙特阿拉伯利雅得国王沙特大学医学城接受减重手术的1633例患者中的111例LSG患者进行了一项回顾性队列研究。患者分为三组：非糖尿病患者、糖尿病前期患者和糖尿病患者。收集了每组患者的人口统计学特征以及术前和术后的BMI和HbA1c值。
结果
患者的平均年龄为41.35±11.8岁，其中56.8%为女性。我们的分析表明，所有三组患者的BMI值术后均有显著且几乎相似的总体下降（平均差异：14.43，p<0.001）。HbA1c水平也显著改善，糖尿病组下降幅度最大（从8.7±1.5降至6.6±1.4，p<0.001），其次是糖尿病前期组（从5.9±0.2降至5.4±0.3，p<0.001）和非糖尿病组（从5.4±0.1降至5.2±0.3，p=0.003）。
结论
LSG可显著改善BMI和HbA1c水平。术后，糖尿病患者的HbA1c百分比下降幅度最大，这支持了LSG在改善代谢健康方面的作用。
