Thakur Sameer
Animal Service Department, Dhangadhi Sub-Metropolitan City Office, Dhangadhi, Nepal.
J Parasit Dis. 2024 Dec;48(4):723-735. doi: 10.1007/s12639-024-01700-3. Epub 2024 Jun 28.
Fasciolosis, caused by and , is a globally prevalent vector-borne disease that affects livestock and humans, with significant economic and zoonotic implications. In Nepal where livestock contributes to 11.5% of the GDP, fasciolosis poses a significant threat to the agriculture sector. The country's diverse geographical and climatic conditions contribute to the widespread prevalence of the disease. Domestic ruminants, including buffalo, cattle, goats, and sheep are extensively affected, with a prevalence rate ranging from 10.25% in goats to 68% in buffalo. The disease also impacts high-altitude regions, affecting even yaks in the Himalayas. Human infections are also on the rise, highlighting the zoonotic nature of the disease. This review provides a comprehensive and in-depth analysis of fasciolosis in Nepal, emphasizing its pathogenesis, epidemiology, and diagnosis. The review also assesses the strategies for controlling fasciolosis in Nepal, including anthelmintic treatments, vector control, and farm management practices. The challenges and limitations of these methods are discussed, underscoring the need for alternative strategies to prevent drug resistance and enhance disease management. Additionally, this paper proposes future directions for the management of fasciolosis in Nepal to provide a comprehensive and effective approach for controlling and managing the disease in the country.
由肝片吸虫和巨片吸虫引起的肝片吸虫病是一种全球流行的媒介传播疾病，影响着家畜和人类，具有重大的经济和人畜共患病影响。在尼泊尔，畜牧业占国内生产总值的11.5%，肝片吸虫病对农业部门构成重大威胁。该国多样的地理和气候条件导致了该病的广泛流行。包括水牛、牛、山羊和绵羊在内的家养反刍动物受到广泛影响，流行率从山羊的10.25%到水牛的68%不等。该病还影响高海拔地区，甚至影响喜马拉雅山脉的牦牛。人类感染也在增加，凸显了该病的人畜共患病性质。本综述对尼泊尔的肝片吸虫病进行了全面深入的分析，强调了其发病机制、流行病学和诊断。该综述还评估了尼泊尔控制肝片吸虫病的策略，包括驱虫治疗、媒介控制和农场管理实践。讨论了这些方法的挑战和局限性，强调需要替代策略以防止耐药性并加强疾病管理。此外，本文提出了尼泊尔肝片吸虫病管理的未来方向，以提供一种全面有效的方法来控制和管理该国的疾病。
