Mohebi Malihe, Aghamolaei Somayeh, Sohrabi Mohammad Reza, Khazan Hooshang, Rostami Ali
Department of Parasitology and Mycology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Department of Parasitology and Mycology, Faculty of Medicine, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran.
J Parasit Dis. 2024 Dec;48(4):944-949. doi: 10.1007/s12639-024-01725-8. Epub 2024 Aug 21.
Toxocariasis is a common zoonotic parasitic disease, primarily caused by the larvae of or . Humans become infected through accidental ingestion of infective eggs in soil contaminated with feces of infected animals, or by consuming undercooked meat from paratenic hosts harboring larvae. This cross-sectional study aimed to evaluate the seroprevalence of spp. in 250 mothers and their 250 neonates referred to selected teaching hospitals affiliated with Shahid Beheshti University of Medical Sciences, Tehran, Iran in 2020. Data were recorded using a specialized questionnaire, and serum and peripheral blood smears (for eosinophil count) were collected. Serum samples were tested using the ELISA serological test for IgG antibodies against spp. The collected data were analyzed using IBM SPSS Statistics software version 21.0. A chi-square test was performed, and a value less than 0.05 was considered statistically significant. Among the 500 participants, 24 cases (4.8%) tested positive for anti- IgG antibodies. Seropositive cases included 6 mothers only (25%), 6 neonates only (25%), and 12 cases both mother and their neonate (50%). Statistical analysis showed a significant relationship between the presence of anti- antibodies and hospital type and nationality ( value < 0.05). However, no significant relationship was found between the presence of antibodies and other demographic variables such as age, sex, eosinophilia, and history of contact with animals in mothers and their neonates ( value > 0.05). This study indicates a substantial rate infection in mothers and neonates, necessitating appropriate preventive measures by the relevant authorities.
弓蛔虫病是一种常见的人畜共患寄生虫病，主要由犬弓首线虫或猫弓首线虫的幼虫引起。人类通过意外摄入被感染动物粪便污染的土壤中的感染性虫卵，或食用携带弓蛔虫幼虫的转续宿主的未煮熟肉类而感染。这项横断面研究旨在评估2020年转诊至伊朗德黑兰沙希德·贝赫什提医科大学附属选定教学医院的250名母亲及其250名新生儿中弓蛔虫属的血清阳性率。使用专门的问卷记录数据，并采集血清和外周血涂片（用于嗜酸性粒细胞计数）。血清样本采用ELISA血清学检测法检测抗弓蛔虫属IgG抗体。使用IBM SPSS Statistics软件21.0版对收集到的数据进行分析。进行卡方检验，P值小于0.05被认为具有统计学意义。在500名参与者中，24例（4.8%）抗弓蛔虫属IgG抗体检测呈阳性。血清阳性病例包括仅6名母亲（25%）、仅6名新生儿（25%）以及12例母亲及其新生儿均为阳性（50%）。统计分析显示，抗弓蛔虫抗体的存在与医院类型和国籍之间存在显著关系（P值<0.05）。然而，在母亲及其新生儿中，抗体的存在与其他人口统计学变量如年龄、性别、嗜酸性粒细胞增多以及与动物接触史之间未发现显著关系（P值>0.05）。这项研究表明母亲和新生儿中弓蛔虫感染率较高，相关当局需要采取适当的预防措施。
