Mansour Somar, Badr Ali, Mansour Majd, Badr Mouhamad, Afif Ali, Rajab Samer, Alshehabi Zuheir
Department of Pathology, Cancer Research Center Tishreen University Hospital Latakia Syria.
Faculty of Medicine, Cancer Research Center Tishreen University Latakia Syria.
Clin Case Rep. 2024 Nov 1;12(11):e9552. doi: 10.1002/ccr3.9552. eCollection 2024 Nov.
Mature mediastinal teratoma (MMT) is a benign tumor that is composed of well-differentiated tissues from all three germ cell layers. Malignant tumors have a distinct feature of adhering to the surrounding organs. Therefore, adhesion of MMT to the adjacent tissues, as a benign tumor, is rare and considered a surgical challenge. It leads to incomplete tumor resection to avoid damage to the surrounding tissues.
MMT is a germ cell tumor that contains well-differentiated tissues from ectodermal, mesodermal, and endodermal germ cell layers. MMT comprises approximately 3%-12% of mediastinal tumors in adults and 60%-70% of mediastinal germ cell tumors. Complete surgical resection is the standard treatment. When adhesion to the surrounding tissues is present, residual tissues could be retained to reduce the injury of the peripheral blood vessels and nerves. We are reporting a rare case of MMT with adhesions to the pericardium and discussing the diagnostic and surgical challenges.
成熟纵隔畸胎瘤（MMT）是一种良性肿瘤，由来自所有三个胚层的分化良好的组织组成。恶性肿瘤具有粘连周围器官的明显特征。因此，作为良性肿瘤的MMT粘连至相邻组织的情况罕见，被视为手术挑战。这会导致肿瘤切除不完全，以避免损伤周围组织。
MMT是一种生殖细胞肿瘤，包含来自外胚层、中胚层和内胚层生殖细胞层的分化良好的组织。MMT约占成人纵隔肿瘤的3%-12%，占纵隔生殖细胞肿瘤的60%-70%。完整手术切除是标准治疗方法。当存在与周围组织的粘连时，可保留残留组织以减少外周血管和神经的损伤。我们报告一例罕见的MMT与心包粘连的病例，并讨论诊断和手术挑战。
