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以慢性腹泻和肠系膜缺血为表现的小肠神经内分泌肿瘤:一例报告

Small bowel neuroendocrine tumor presenting with chronic diarrhea and mesenteric ischemia: A case report.

作者信息

Sawaf Bisher, Abbarh Shahem, Ahmed Ashraf I, Halabiya Malik, Ismail Abdellatif, Mezhoud Souraia

机构信息

Department of Internal Medicine, Division of Gastroenterology and Hepatology Hamad Medical Corporation Doha Qatar.

Department of Internal Medicine University of Toledo Medical Center Toledo Ohio USA.

出版信息

Clin Case Rep. 2024 Oct 31;12(11):e9508. doi: 10.1002/ccr3.9508. eCollection 2024 Nov.

Abstract

KEY CLINICAL MESSAGE

The diagnosis of gastrointestinal neuroendocrine tumors is often challenging owing to the nonspecific presentation. This may lead to delayed diagnosis and serious, rare complications, such as acute mesenteric ischemia. This case highlights the importance of early recognition and the need for a multidisciplinary approach to managing such cases.

ABSTRACT

Gastrointestinal (GI) neuroendocrine tumors (NETs) are rare neoplasms originating from neuroendocrine cells within the digestive tract. Despite their rarity, their incidence is increasing, necessitating a better understanding of their presentation and management. In the present report, we present a case of duodenal bulb NET that caused chronic diarrhea and unintentional weight loss for 2 years before manifesting as acute mesenteric ischemia. This case sheds light on the diagnostic challenges associated with GI NETs, particularly in cases with nonspecific symptoms. In addition, it underscores the importance of prompt recognition and management, as evidenced by the progression of the patient to acute mesenteric ischemia.

摘要

关键临床信息

由于临床表现不具特异性,胃肠道神经内分泌肿瘤的诊断往往具有挑战性。这可能导致诊断延迟以及严重的罕见并发症,如急性肠系膜缺血。本病例突出了早期识别的重要性以及对此类病例采用多学科方法管理的必要性。

摘要

胃肠道神经内分泌肿瘤(NETs)是起源于消化道神经内分泌细胞的罕见肿瘤。尽管它们罕见,但发病率正在上升,因此有必要更好地了解其临床表现和管理方法。在本报告中,我们呈现了一例十二指肠球部NET病例,该病例在表现为急性肠系膜缺血之前,导致慢性腹泻和非故意体重减轻达2年之久。本病例揭示了与胃肠道NETs相关的诊断挑战,尤其是在症状不具特异性的病例中。此外,它强调了及时识别和管理的重要性,患者进展为急性肠系膜缺血就证明了这一点。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/03b8/11527732/09378b8ca072/CCR3-12-e9508-g002.jpg

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