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儿童罕见枕叶节细胞胶质瘤:MRI在诊断和治疗中的关键作用

Uncommon occipital ganglioglioma in a child: The critical role of MRI in diagnosis and management.

作者信息

Flynn Jeannie, Gunawan Prastiya Indra, Noviandi Riza, Samosir Sunny Mariana

机构信息

Department of Child Health, Dr Soetomo General Academic Hospital, Surabaya, Indonesia.

Department of Child Health, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia.

出版信息

Radiol Case Rep. 2024 Oct 15;20(1):124-128. doi: 10.1016/j.radcr.2024.09.131. eCollection 2025 Jan.

DOI:10.1016/j.radcr.2024.09.131
PMID:39493940
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11528231/
Abstract

Epilepsy is a prevalent neurological disorder in children, with 30-35% of cases developing into intractable epilepsy despite appropriate anti-seizure medications (ASMs). Advanced imaging is crucial for early diagnosis, especially in detecting structural causes like gangliogliomas, which are associated with drug-resistant focal epilepsy. We report a 5-year-old boy with recurrent seizures, initially undetected by EEG. Persistent seizures led to the identification of an occipital lobe ganglioglioma through MRI. The tumor was successfully resected, significantly improving the patient's condition. This case emphasizes the limitations of relying solely on EEG for epilepsy diagnosis and highlights the necessity of integrating advanced imaging techniques. The successful outcome underscores the importance of a multidisciplinary approach, involving pediatric neurologists, radiologists, and neurosurgeons, in managing complex pediatric epilepsy cases.

摘要

癫痫是儿童中一种常见的神经系统疾病,尽管使用了适当的抗癫痫药物(ASMs),仍有30%至35%的病例发展为难治性癫痫。先进的影像学检查对于早期诊断至关重要,特别是在检测如神经节胶质瘤等结构性病因方面,这些病因与耐药性局灶性癫痫有关。我们报告了一名5岁男孩,反复癫痫发作,最初脑电图未检测到异常。持续性癫痫发作通过磁共振成像(MRI)发现了枕叶神经节胶质瘤。肿瘤成功切除,患者病情显著改善。该病例强调了仅依靠脑电图进行癫痫诊断的局限性,并突出了整合先进影像学技术的必要性。成功的结果强调了多学科方法的重要性,包括儿科神经科医生、放射科医生和神经外科医生,以管理复杂的儿科癫痫病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1717/11528231/2615bea52506/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1717/11528231/1720f85e877e/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1717/11528231/53b107e95053/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1717/11528231/1c6dd640b893/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1717/11528231/2615bea52506/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1717/11528231/1720f85e877e/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1717/11528231/53b107e95053/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1717/11528231/1c6dd640b893/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1717/11528231/2615bea52506/gr4.jpg

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Uncommon occipital ganglioglioma in a child: The critical role of MRI in diagnosis and management.儿童罕见枕叶节细胞胶质瘤:MRI在诊断和治疗中的关键作用
Radiol Case Rep. 2024 Oct 15;20(1):124-128. doi: 10.1016/j.radcr.2024.09.131. eCollection 2025 Jan.
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Ganglioglioma and intractable epilepsy: clinical and neurophysiologic features and predictors of outcome after surgery.神经节胶质瘤与难治性癫痫:临床及神经生理学特征以及手术预后的预测因素
Epilepsia. 1998 Mar;39(3):307-13. doi: 10.1111/j.1528-1157.1998.tb01378.x.

本文引用的文献

1
An individual data-driven virtual resection model based on epileptic network dynamics in children with intractable epilepsy: a magnetoencephalography interictal activity application.基于难治性癫痫患儿癫痫网络动力学的个体数据驱动虚拟切除模型:脑磁图发作间期活动应用
Brain Commun. 2023 May 25;5(3):fcad168. doi: 10.1093/braincomms/fcad168. eCollection 2023.
2
Clinical Factors Related to Outcomes in Pediatric Epilepsy Surgery: Insight into Predictors of Poor Surgical Outcome.与儿科癫痫手术结果相关的临床因素:对手术不良结果预测因素的深入了解。
Neurol Med Chir (Tokyo). 2023 May 15;63(5):173-178. doi: 10.2176/jns-nmc.2022-0300. Epub 2023 Apr 6.
3
Seizure outcomes and prognostic factors in patients with gangliogliomas associated with epilepsy.
伴有癫痫的神经节细胞胶质瘤患者的癫痫发作结局及预后因素
Front Surg. 2022 Aug 11;9:946201. doi: 10.3389/fsurg.2022.946201. eCollection 2022.
4
Precision medicine in pediatric temporal epilepsy surgery: optimization of outcomes through functional MRI memory tasks and tailored surgeries.儿童颞叶癫痫手术中的精准医学:通过功能磁共振成像记忆任务和个性化手术优化治疗效果
J Neurosurg Pediatr. 2022 Jul 1;30(3):272-283. doi: 10.3171/2022.5.PEDS22148. Print 2022 Sep 1.
5
Magnetic resonance imaging findings in children with intractable epilepsy compared to children with medical responsive epilepsy.与药物反应性癫痫患儿相比,难治性癫痫患儿的磁共振成像结果。
Iran J Child Neurol. 2022 Spring;16(2):53-61. doi: 10.22037/ijcn.v16i2.2710. Epub 2022 Mar 14.
6
Negative or positive imaging: ganglioglioma in a boy with epilepsy.影像学阴性或阳性:癫痫男孩的神经节胶质瘤。
Br J Neurosurg. 2024 Aug;38(4):1035-1037. doi: 10.1080/02688697.2021.2005776. Epub 2021 Nov 25.
7
Epilepsy outcome following resection of low-grade brain tumors in children.儿童低级别脑肿瘤切除术后的癫痫结局
J Neurosurg Pediatr. 2019 Jun 1;23(6):726–731. doi: 10.3171/2019.1.PEDS18367. Epub 2019 Mar 22.
8
Resting-state functional MRI connectivity impact on epilepsy surgery plan and surgical candidacy: prospective clinical work.静息态功能磁共振成像连接性对癫痫手术计划和手术候选资格的影响:前瞻性临床研究
J Neurosurg Pediatr. 2020 Mar 20;25(6):574-581. doi: 10.3171/2020.1.PEDS19695. Print 2020 Jun 1.
9
Seizure outcome of pediatric epilepsy surgery: Systematic review and meta-analyses.小儿癫痫手术的癫痫发作结局:系统评价和荟萃分析。
Neurology. 2020 Feb 18;94(7):311-321. doi: 10.1212/WNL.0000000000008966. Epub 2020 Jan 29.