Department of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University, Seoul 05029, Republic of Korea (Hyun); Ieul Animal Clinic, Seoul 06580, Republic of Korea (Hwang S-H); Laboratory of Veterinary Dermatology and the Research Institute for Veterinary Science, College of Veterinary Medicine, Seoul National University, Seoul 08826, Republic of Korea (Hwang C-Y).
Can Vet J. 2024 Nov;65(11):1131-1135.
An 8-year-old spayed female Maltese dog was referred with a 4-month history of multifocal pruritic erosive or ulcerative lesions on the head, ventral neck, chest, and abdomen; and chronic otitis externa. Biopsy revealed cytotoxic dermatitis and apoptotic keratinocytes with occasional lymphocytic satellitosis. Bacterial culture and antimicrobial susceptibility tests revealed multidrug-resistant infection of the skin and ears. The skin lesions regressed after treatment of infection with ciprofloxacin. Based on the skin lesions, histological characteristics, and response to therapy, the dog was presumed to have erythema multiforme induced by infection. This case report emphasizes that infection could be a trigger of erythema multiforme in dogs. Key clinical message: Erythema multiforme caused by infection is rare and poorly characterized in the veterinary literature. This case report describes the clinical characteristics of, diagnostic approach to, and treatment of erythema multiforme caused by .
一只 8 岁已绝育的雌性马尔济斯犬因头部、颈腹侧、胸部和腹部多灶性瘙痒性糜烂或溃疡性病变和慢性外耳炎而被转介。活检显示细胞毒性皮炎和凋亡角质形成细胞，偶尔伴有淋巴细胞卫星现象。细菌培养和药敏试验显示皮肤和耳朵的多重耐药感染。皮肤病变在用环丙沙星治疗感染后消退。根据皮肤病变、组织学特征和治疗反应，该犬被推测患有感染引起的多形红斑。本病例报告强调感染可能是犬多形红斑的触发因素。关键临床信息：感染引起的多形红斑在兽医文献中罕见且特征描述不佳。本病例报告描述了感染引起的多形红斑的临床特征、诊断方法和治疗方法。
