Department of Veterinary Pathology, Western College of Veterinary Medicine, University of Saskatchewan, 52 Campus Drive, Saskatoon, Saskatchewan S7N 5B4 (Rose, Wobeser); Department of Veterinary Clinical and Diagnostic Sciences, University of Calgary Faculty of Veterinary Medicine, 3280 Hospital Drive NW, Calgary, Alberta T2N 4Z6 (Pang, Davies); Animal Health Centre, 1767 Angus Campbell Road, Abbotsford, British Columbia V3G 2M3 (McGregor); Animal Health Laboratory, University of Guelph, 419 Gordon Street, Guelph, Ontario N1G 2W1 (Rossi).
Can Vet J. 2024 Nov;65(11):1157-1164.
Perianesthetic death or sedation death in companion animals is an infrequent but devastating complication. Few studies have investigated the pathology associated with these deaths.
To determine clinical features and postmortem findings for submissions to multiple Canadian diagnostic laboratories from perianesthetic/sedation deaths in dogs and cats.
Laboratory Information Management Systems were retrospectively reviewed for cases of perianesthetic/sedation death in dogs and cats. Inclusion criteria were: i) whole-body submissions and ii) death within 7 d after the procedure.
Pathology reports determined the cause of death in 43% of dogs (73/168) and 34% of cats (50/147). Spay/neuter surgeries were the most common procedure for which animals were submitted (dogs: = 72, 31%; cats: = 111, 58%). The American Society of Anesthesiologists physical status in these animals was low (ASA status I or II) in 94% of dogs (68/72) and 93% of cats (103/111). Clinical history was considered incomplete in 60.3% of cases (242/401).
These results had similar trends to those in previous studies that identified an important proportion of submissions for perianesthetic/sedation deaths lacked significant lesions to explain the cause of death. This study also identified spay/neuter procedures were involved in the largest proportion of submissions, despite their low pre-anesthetic/sedation risk.
围手术期/镇静死亡是伴侣动物中一种罕见但破坏性极大的并发症。很少有研究调查与这些死亡相关的病理学。
确定加拿大多个诊断实验室因犬猫围手术期/镇静死亡而提交的病例的临床特征和尸检结果。
回顾性审查了犬猫围手术期/镇静死亡的实验室信息管理系统病例。纳入标准为：i）全身提交和 ii）在手术 7 天内死亡。
病理报告确定了 43%的犬（73/168）和 34%的猫（50/147）的死因。绝育手术是提交动物最常见的程序（犬：=72，31%；猫：=111，58%）。这些动物的美国麻醉师协会身体状况为低（ASA 状态 I 或 II），犬为 94%（68/72），猫为 93%（103/111）。60.3%的病例（242/401）的临床病史被认为不完整。
这些结果与之前的研究相似，这些研究表明，很大一部分提交的围手术期/镇静死亡病例缺乏明显的病变来解释死亡原因。本研究还发现，绝育手术尽管在麻醉前/镇静前的风险较低，但在提交的病例中占比最大。
