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与莱索托马塞卢卫生机构结核病患者不良治疗结果相关的因素。

Factors associated with unfavourable treatment outcomes among tuberculosis patients at health facilities of Maseru, Lesotho.

机构信息

Department of Public Health, Faculty of Health Sciences, Sefako Makgatho Health Sciences University, Pretoria.

出版信息

S Afr Fam Pract (2004). 2024 Oct 21;66(1):e1-e6. doi: 10.4102/safp.v66i1.6004.

Abstract

Tuberculosis (TB) treatment success rates (TSR) remain low in Lesotho. The country achieved TSR of 76% in 2020, which is far below the World Health Organization's 95% target set for 2030. This study determined the level of treatment success and factors associated with unfavourable treatment outcomes. This descriptive cross-sectional study used patient records to perform descriptive and logistic regression analyses. Sixty-one per cent of the 336 TB patients were male. Two hundred and eighty-nine had favourable outcomes, of which 10% died in the course of treatment. Patients ≤ 44 years old, and those with supported treatment, had lower odds of unfavourable treatment outcomes, respectively, adjusted odds ration [aOR] = 0.39 (95% CI: 0.19-0.78) and aOR = 0.22 (95% CI: 0.08-0.62), p  0.05.Contribution: The death of patients while on TB treatment needs to be addressed, including heightened advocacy for supported treatment.

摘要

在莱索托,结核病(TB)的治疗成功率(TSR)仍然很低。该国在 2020 年实现了 76%的 TSR,远低于世界卫生组织设定的到 2030 年达到 95%的目标。本研究旨在确定治疗成功的水平以及与不良治疗结果相关的因素。这项描述性的横断面研究使用患者记录进行描述性和逻辑回归分析。336 名结核病患者中,61%为男性。289 名患者的治疗结果良好,其中 10%在治疗过程中死亡。年龄≤44 岁的患者和接受支持性治疗的患者,其不良治疗结局的几率较低,调整后的比值比(aOR)分别为 0.39(95%可信区间:0.19-0.78)和 0.22(95%可信区间:0.08-0.62),p<0.05。贡献:需要解决结核病治疗期间患者死亡的问题,包括加强对支持性治疗的宣传。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5caf/11538129/b16bf5612064/SAFP-66-6004-g001.jpg

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