Department of Public Health, Faculty of Health Sciences, Sefako Makgatho Health Sciences University, Pretoria.
S Afr Fam Pract (2004). 2024 Oct 21;66(1):e1-e6. doi: 10.4102/safp.v66i1.6004.
Tuberculosis (TB) treatment success rates (TSR) remain low in Lesotho. The country achieved TSR of 76% in 2020, which is far below the World Health Organization's 95% target set for 2030. This study determined the level of treatment success and factors associated with unfavourable treatment outcomes. This descriptive cross-sectional study used patient records to perform descriptive and logistic regression analyses. Sixty-one per cent of the 336 TB patients were male. Two hundred and eighty-nine had favourable outcomes, of which 10% died in the course of treatment. Patients ≤ 44 years old, and those with supported treatment, had lower odds of unfavourable treatment outcomes, respectively, adjusted odds ration [aOR] = 0.39 (95% CI: 0.19-0.78) and aOR = 0.22 (95% CI: 0.08-0.62), p 0.05.Contribution: The death of patients while on TB treatment needs to be addressed, including heightened advocacy for supported treatment.
在莱索托，结核病（TB）的治疗成功率（TSR）仍然很低。该国在 2020 年实现了 76%的 TSR，远低于世界卫生组织设定的到 2030 年达到 95%的目标。本研究旨在确定治疗成功的水平以及与不良治疗结果相关的因素。这项描述性的横断面研究使用患者记录进行描述性和逻辑回归分析。336 名结核病患者中，61%为男性。289 名患者的治疗结果良好，其中 10%在治疗过程中死亡。年龄≤44 岁的患者和接受支持性治疗的患者，其不良治疗结局的几率较低，调整后的比值比（aOR）分别为 0.39（95%可信区间：0.19-0.78）和 0.22（95%可信区间：0.08-0.62），p<0.05。贡献：需要解决结核病治疗期间患者死亡的问题，包括加强对支持性治疗的宣传。
