Department of Transfusion, The Second Affiliated Hospital of Xiamen Medical College, Xiamen, China.
Department of Otorhinolaryngology-Head & Neck Surgery, The Second Affiliated Hospital of Xiamen Medical College, Xiamen, China.
Medicine (Baltimore). 2024 Nov 1;103(44):e40326. doi: 10.1097/MD.0000000000040326.
Anemia affects a third of the world's population and contributes to increased morbidity and mortality, decreased work productivity, and impaired neurological development. In recent years, many studies have found a possible association between anemia and sensorineural hearing loss (SNHL), especially in various types of nutritional deficiency and hemoglobin disorders anemia. Anemia may affect hearing through various mechanisms, including affecting microcirculation in the ear, causing tissue hypoxia in the ear, and through inflammatory and oxidative stress pathways. This review aims to comprehensively analyze the association between various types of anemia and SNHL, including possible biological mechanisms, clinical features, and treatment strategies, and clarify the importance of anemia treatment and management in preventing SNHL.
贫血影响了全球三分之一的人口,并导致发病率和死亡率上升、工作生产力下降以及神经发育受损。近年来,许多研究发现贫血与感音神经性听力损失(SNHL)之间可能存在关联,尤其是在各种类型的营养缺乏和血红蛋白紊乱性贫血中。贫血可能通过多种机制影响听力,包括影响耳部微循环、导致耳部组织缺氧以及通过炎症和氧化应激途径。本综述旨在全面分析各种类型的贫血与 SNHL 之间的关联,包括可能的生物学机制、临床特征和治疗策略,并阐明贫血治疗和管理在预防 SNHL 中的重要性。