一种新的抗肿瘤抗生素——色霉素。I. 产生菌的分类学研究：链霉菌属的一个新亚种

A new antitumor antibiotic, chromoxymycin. I. Taxonomic studies on the producing strain: a new subspecies of the genus Streptomyces.

作者信息

Iwami M, Kawai Y, Kiyoto S, Terano H, Kohsaka M, Aoki H, Imanaka H

出版信息

J Antibiot (Tokyo). 1986 Jan;39(1):6-11. doi: 10.7164/antibiotics.39.6.

DOI:10.7164/antibiotics.39.6

Abstract

A new subspecies of the genus Streptomyces, for which the name S. libani subsp. rubropurpureus subsp. nov. is proposed, is described. Soil isolate, strain No. 6362, produces a new antitumor substance chromoxymycin. The strain has a gray or red spore mass color, spiral spore chains with smooth spores, is nonchromogenic, and utilizes most carbon sources. Strain No. 6362 is most closely related to S. libani, although there are differences in colorization of reverse colony and spore chain morphology between each other. Those differences are not enough to establish a new species. It is suitable to consider that strain No. 6362 is identified as a new subspecies in the species of S. libani.

摘要

描述了链霉菌属的一个新亚种，提议将其命名为黎巴嫩链霉菌红色紫亚种（Streptomyces libani subsp. rubropurpureus subsp. nov.）。土壤分离株6362号产生一种新的抗肿瘤物质色霉素。该菌株的孢子堆颜色为灰色或红色，孢子链呈螺旋状，孢子光滑，不产色素，能利用大多数碳源。6362号菌株与黎巴嫩链霉菌关系最为密切，尽管它们在菌落背面颜色和孢子链形态上存在差异。但这些差异不足以确立一个新物种。适宜认为6362号菌株被鉴定为黎巴嫩链霉菌种内的一个新亚种。