Hatanaka H, Iwami M, Kino T, Goto T, Okuhara M
Exploratory Research Laboratories, Fujisawa Pharmaceutical Co., Ltd., Ibaraki, Japan.
J Antibiot (Tokyo). 1988 Nov;41(11):1586-91. doi: 10.7164/antibiotics.41.1586.
A new subspecies of the genus Streptomyces, the proposed name of which is Streptomyces hygroscopicus subsp. yakushimaensis subsp. nov., is described. Soil isolate, strain No. 7238, produces the novel immunosuppressants, FR-900520 and FR-900523. The organism is characterized by its gray aerial mycelium color, hygroscopic spore mass and spiral spore chains with warty or spiny spore surfaces. It is nonchromogenic. Strain No. 7238 shows characteristics most closely related to Streptomyces antimycoticus and S. hygroscopicus, although there are differences in physiological characteristics and carbohydrate utilization. In terms of morphological characteristics, strain No. 7238 is different from S. antimycoticus, but resembles S. hygroscopicus. The differences are not sufficient to establish a new species. It would be most suitable to designate strain No. 7238 as a new subspecies within the species of S. hygroscopicus.
描述了链霉菌属的一个新亚种，其暂定名称为吸水链霉菌雅库什亚种（Streptomyces hygroscopicus subsp. yakushimaensis subsp. nov.）。土壤分离株7238号产生新型免疫抑制剂FR - 900520和FR - 900523。该菌株的特征为灰色气生菌丝体颜色、吸湿孢子团以及具瘤状或刺状孢子表面的螺旋状孢子链。它不产色素。7238号菌株显示出与抗真菌链霉菌和吸水链霉菌关系最为密切的特征，尽管在生理特征和碳水化合物利用方面存在差异。就形态特征而言，7238号菌株与抗真菌链霉菌不同，但与吸水链霉菌相似。这些差异不足以确立一个新物种。将7238号菌株指定为吸水链霉菌物种内的一个新亚种最为合适。
