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安大略省北部与南部接受常见中高风险择期手术患者的术后结局:一项基于人群的队列研究。

Postoperative outcomes among Northern versus Southern Ontario patients undergoing common intermediate- to high-risk elective surgeries: a population-based cohort study.

作者信息

Chen Max, Duncan Kaitlin, Talarico Robert, McIsaac Sarah, McIsaac Daniel I

机构信息

Northern Ontario School of Medicine University, Sudbury, ON, Canada.

Department of Anesthesiology, Health Sciences North, Sudbury, ON, Canada.

出版信息

Can J Anaesth. 2024 Dec;71(12):1705-1715. doi: 10.1007/s12630-024-02860-9. Epub 2024 Nov 4.

DOI:10.1007/s12630-024-02860-9
PMID:39497003
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11666767/
Abstract

PURPOSE

Northern Ontario residents experience multiple health disparities compared with those in Southern Ontario. It is unknown whether this leads to differences in surgical outcomes. We sought to compare postoperative outcomes of patients from Northern and Southern Ontario.

METHODS

We conducted a retrospective population-based cohort study using linked administrative health care data to identify all adult patients undergoing selected elective intermediate- to high-risk noncardiac surgeries in Ontario, Canada between 2009 and 2022. The primary outcome was 30-day mortality following surgery. The secondary outcomes were number of days alive at home, hospital length of stay, total health care system costs, discharge disposition, and readmissions. We used regression models to estimate the adjusted association between the exposure and outcomes.

RESULTS

This study identified 562,115 patients, including 41,191 (7.3%) from Northern Ontario. We did not find strong evidence that mortality rates were higher for Northern vs Southern Ontario residents (adjusted odds ratio, 1.04; 95% confidence interval [CI], 0.85 to 1.27). Health system costs were lower for Northern Ontario residents at 30 days [adjusted ratio of mean (RoM), 0.92; 95% CI, 0.89 to 0.96] and at 365 days (adjusted RoM, 0.93; 95% CI, 0.90 to 0.96). Hospital length of stay was longer for Northern Ontario residents (adjusted RoM, 1.06; 95% CI, 1.01 to 1.11). The number of days alive at home and rate of readmission were not statistically different between the two groups.

CONCLUSION

Northern Ontario residency was not associated with increased odds of mortality after intermediate- to high-risk elective noncardiac surgery. Overall, we found no clinically meaningful differences in postoperative outcomes between patients from Northern and Southern Ontario.

摘要

目的

与安大略省南部居民相比,安大略省北部居民面临多种健康差异。尚不清楚这是否会导致手术结果的差异。我们试图比较安大略省北部和南部患者的术后结果。

方法

我们进行了一项基于人群的回顾性队列研究,使用关联的行政医疗保健数据来识别2009年至2022年期间在加拿大安大略省接受选定的择期中等至高危非心脏手术的所有成年患者。主要结局是术后30天死亡率。次要结局包括在家存活天数、住院时间、医疗保健系统总费用、出院处置情况和再入院情况。我们使用回归模型来估计暴露因素与结局之间的校正关联。

结果

本研究共纳入562,115例患者,其中41,191例(7.3%)来自安大略省北部。我们没有发现有力证据表明安大略省北部居民的死亡率高于南部居民(校正比值比,1.04;95%置信区间[CI],0.85至1.27)。安大略省北部居民在30天时的医疗系统费用较低[校正平均比值(RoM),0.92;95%CI,0.89至0.96],在365天时也是如此(校正RoM,0.93;95%CI,0.90至0.96)。安大略省北部居民的住院时间更长(校正RoM,1.06;95%CI,1.01至1.11)。两组在家存活天数和再入院率在统计学上没有差异。

结论

安大略省北部居民身份与中等至高危择期非心脏手术后死亡率增加无关。总体而言,我们发现安大略省北部和南部患者的术后结果在临床上没有有意义的差异。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d1b/11666767/e2911acaffb2/12630_2024_2860_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d1b/11666767/1f5de2a15a51/12630_2024_2860_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d1b/11666767/fd4c0992bfae/12630_2024_2860_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d1b/11666767/e2911acaffb2/12630_2024_2860_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d1b/11666767/1f5de2a15a51/12630_2024_2860_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d1b/11666767/fd4c0992bfae/12630_2024_2860_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d1b/11666767/e2911acaffb2/12630_2024_2860_Fig3_HTML.jpg

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本文引用的文献

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