Sibley Stephanie, Atzema Clare, Balik Martin, Bedford Jonathan, Conen David, Garside Tessa, Johnston Brian, Kanji Salmaan, Landry Camron, McIntyre William, Maslove David M, Muscedere John, Ostermann Marlies, Scheuemeyer Frank, Seeley Andrew, Sivilotti Marco, Tsang Jennifer, Wang Michael K, Welters Ingeborg, Walkey Allan, Cuthbertson Brian
Department of Critical Care Medicine, Queen's University, 76 Stuart Street, Kingston, ON, K7L 2V7, Canada.
Department of Medicine, University of Toronto, Toronto, Canada.
BMC Proc. 2024 Nov 5;18(Suppl 22):23. doi: 10.1186/s12919-024-00309-x.
Atrial fibrillation (AF) is a common arrhythmia encountered in acute and critical illness and is associated with poor short and long-term outcomes. Given the consequences of developing AF, research into prevention, prediction and treatment of this arrhythmia in the critically ill are of great potential benefit, however, study of AF in critically ill patients faces unique challenges, leading to a sparse evidence base to guide management in this population. Major obstacles to the study of AF in acute and critical illness include absence of a common definition, challenges in designing studies that capture complex etiology and assess causality, lack of a clear outcome set, difficulites in recruitment in acute environments with respect to timing, consent, and workflow, and failure to embed studies into clinical care platforms and capitalize on emerging technologies. Collaborative effort by researchers, clinicians, and stakeholders should be undertaken to address these challenges, both through interdisciplinary cooperation for the optimization of research efficiency and advocacy to advance the understanding of this common and complex arrhythmia, resulting in improved patient care and outcomes. The Symposium on Atrial Fibrillation in Acute and Critical Care was convened to address some of these challenges and propose potential solutions.
心房颤动（AF）是急性和危重症中常见的心律失常，与短期和长期不良预后相关。鉴于发生AF的后果，对危重症患者中这种心律失常的预防、预测和治疗进行研究具有巨大的潜在益处。然而，对危重症患者AF的研究面临独特挑战，导致指导该人群管理的证据基础薄弱。急性和危重症中AF研究的主要障碍包括缺乏统一的定义、设计能够捕捉复杂病因并评估因果关系的研究存在挑战、缺乏明确的结局指标集、在急性环境中招募患者在时间安排、同意和工作流程方面存在困难，以及未能将研究纳入临床护理平台并利用新兴技术。研究人员、临床医生和利益相关者应共同努力应对这些挑战，通过跨学科合作优化研究效率，并倡导增进对这种常见且复杂心律失常的理解，从而改善患者护理和预后。召开急性和危重症心房颤动研讨会就是为了解决其中一些挑战并提出潜在解决方案。
