青年期前发病的炎症性肠病患者的劳动力市场参与度和收入——疾病严重程度和心理健康的作用

Labor Market Participation and Income in Patients With Inflammatory Bowel Disease Onset Before Young Adulthood-The Role of Disease Severity and Mental Health.

作者信息

Rasmussen Julie, Nørgård Bente Mertz, Bøggild Henrik, Qvist Niels, Everhov Åsa H, Malmborg Petter, Nielsen Rasmus Gaardskær, Brund René Børge Korsgaard, Fonager Kirsten

机构信息

Department of Social Medicine, Aalborg University Hospital, Aalborg, Denmark.

Department of Clinical Medicine, Aalborg University, Gistrup, Denmark.

出版信息

J Crohns Colitis. 2025 Apr 4;19(4). doi: 10.1093/ecco-jcc/jjae165.

DOI:10.1093/ecco-jcc/jjae165

PMID:39497559

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12001340/

Abstract

BACKGROUND AND AIMS

Only few studies have examined the socioeconomic consequences of being diagnosed with inflammatory bowel disease (IBD) in childhood or youth. Disease severity has been linked to lower earnings, but little attention has been paid to comorbid mental health conditions. The aim is to examine labor market participation (LMP) and income in patients with IBD onset in childhood or youth and examine how disease severity and mental health conditions affect LMP.

METHODS

In this register-based cohort study, we included patients with IBD onset before 25 years of age and matched comparators. We estimated the relative risk (RR) of having low LMP and the median yearly income from ages 26 to 30. RR of low LMP was also assessed in subgroups of patients based on disease severity (severe/nonsevere) and mental health conditions (yes/no).

RESULTS

A total of 3398 patients with IBD and 28 207 comparators were included. Overall, patients with IBD more often had low LMP (16.4% vs 14.4% in comparators), but slightly higher income (median yearly income difference at age 30: 1141 Euro [95% CI, 483-1798]). In subgroup analyses, only patients with severe IBD had a higher risk of low LMP (RR: 1.46 [95% CI, 1.23-1.72]), whereas patients with nonsevere IBD did not. Among patients with severe disease and mental health conditions, 46% had low LMP (RR: 5.03 [95% CI, 4.38-5.78]).

CONCLUSIONS

Patients with IBD more often had low LMP, but their income was not affected. The subgroup of patients with severe disease and mental health conditions had the highest risk of low LMP.

摘要

背景与目的

仅有少数研究探讨了儿童期或青年期被诊断为炎症性肠病（IBD）的社会经济后果。疾病严重程度与收入较低有关，但对合并的心理健康状况关注较少。目的是研究儿童期或青年期发病的IBD患者的劳动力市场参与情况（LMP）和收入，并探讨疾病严重程度和心理健康状况如何影响LMP。

方法

在这项基于登记的队列研究中，我们纳入了25岁之前发病的IBD患者以及匹配的对照者。我们估计了LMP较低的相对风险（RR）以及26至30岁的年中位数收入。还根据疾病严重程度（严重/非严重）和心理健康状况（有/无）在患者亚组中评估了LMP较低的RR。

结果

共纳入了3398例IBD患者和28207例对照者。总体而言，IBD患者LMP较低的情况更为常见（对照者中为14.4%，IBD患者中为16.4%），但收入略高（30岁时的年中位数收入差异：1141欧元[95%CI，483 - 1798]）。在亚组分析中，只有重症IBD患者LMP较低的风险较高（RR：1.46[95%CI，1.23 - 1.72]），而非重症IBD患者则没有。在患有严重疾病和心理健康问题的患者中，46%的患者LMP较低（RR：5.03[95%CI，4.38 - 5.78]）。