青少年和青年癌症幸存者中的经济毒性：对教育程度、就业和收入的系统评价。
Financial toxicity among adolescent and young adult cancer survivors: A systematic review of educational attainment, employment, and income.
作者信息
Di Giuseppe Giancarlo, Pagalan Lief, Jetha Arif, Pechlivanoglou Petros, Pole Jason D
机构信息
Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada.
Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada.
出版信息
Crit Rev Oncol Hematol. 2023 Mar;183:103914. doi: 10.1016/j.critrevonc.2023.103914. Epub 2023 Jan 25.
PURPOSE
To identify, evaluate and summarize the evidence on educational attainment, employment status and income of AYAs surviving cancer.
METHODS
A search of six databases for articles published between 01/01/2010 and 03/31/2022 was performed. Articles with an AYA survivorship population, quantitative design and a cancer-free comparator group were included. Data extraction was conducted, and quality appraisal was completed using ROBINS-I. Results were summarized using a narrative synthesis.
RESULTS
A total of 2801 articles were identified, of which 12 were included. Among the limited evidence, educational attainment did not differ from cancer-free peers. Survivors were more likely to be unemployed, have lower incomes and require social security for income supplementation. Evidence suggested that females, diagnosis of brain cancer and the presence of late-effects were among the risk factors for severe outcomes.
CONCLUSIONS
Limited socioeconomic evidence exists for AYAs surviving cancer. Long-lasting financial toxicities occur and highlights a need for further investigation.
目的
识别、评估和总结癌症存活青少年和青年成人（AYA）的教育程度、就业状况和收入方面的证据。
方法
检索了六个数据库，以查找2010年1月1日至2022年3月31日期间发表的文章。纳入了有AYA存活人群、定量设计且有癌症-free对照组的文章。进行了数据提取，并使用ROBINS-I完成了质量评估。结果采用叙述性综合进行总结。
结果
共识别出2801篇文章，其中12篇被纳入。在有限的证据中，教育程度与无癌症同龄人没有差异。幸存者更有可能失业、收入较低且需要社会保障来补充收入。证据表明，女性、脑癌诊断和后期效应的存在是严重后果的风险因素。
结论
关于癌症存活AYA的社会经济证据有限。存在长期的经济毒性，突出了进一步调查的必要性。
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