Orui Masatsugu, Obara Taku, Ishikuro Mami, Noda Aoi, Shinoda Genki, Murakami Keiko, Iwama Noriyuki, Chiba Ippei, Nakaya Kumi, Hatanaka Rieko, Kogure Mana, Kobayashi Natsuko, Kikuchi Saya, Metoki Hirohito, Kikuya Masahiro, Nakaya Naoki, Hozawa Atsushi, Tomita Hiroaki, Kuriyama Shinichi
Tohoku Medical Megabank Organization, Tohoku University Sendai Japan.
Graduate School of Medicine, Tohoku University Sendai Japan.
PCN Rep. 2024 Nov 4;3(4):e70025. doi: 10.1002/pcn5.70025. eCollection 2024 Dec.
The aim of this study was to evaluate depression at 6 and 12 months postpartum, using the Edinburgh Postpartum Depression Scale (EPDS) total score and its subitem regarding self-harm ideation (SHI) at 1 month postpartum.
A sample of 12,358 postpartum women answered the EPDS and questionaries at 1, 6, and 12 months postpartum longitudinally.
For participants with postpartum depression (PPD; EPDS total score ≥9) and SHI (SHI sub-score ≥1) at 1 month postpartum, the risk of depression at 6 and 12 months postpartum (odds ratio [95% confidence interval] at 6 and 12 months postpartum: 20.03 [16.8-23.8] and 14.55 [12.3-17.2], respectively) was higher than for those with PPD but without SHI at 1 month postpartum (OR: 8.57 [7.36-10.0], and 6.24 [5.38-7.24], respectively). Additionally, SHI even without depressive symptoms at 1 month postpartum is also a risk for depression at 6 and 12 months postpartum. To support our longitudinal evaluation of depression at 6 and 12 months postpartum, these related factors were examined: traumatic events or relocations after the Great East Japan Earthquake, employment status, household income, personality traits, sleep status, psychological distress, and social networks. The result showed employment status, low household income and poor social networks were significantly associated with depression at 12 months postpartum but not at 6 months postpartum.
This study showed a high risk of depression at 6 and 12 months postpartum for those who had depressive symptoms with SHI at 1 month postpartum. Our findings may contribute to the precise evaluation of depression at 6 and 12 months postpartum while considering sleep status, psychological distress and social network during pregnancy.
本研究旨在使用爱丁堡产后抑郁量表（EPDS）总分及其关于产后1个月自伤意念（SHI）的子项目，评估产后6个月和12个月时的抑郁情况。
12358名产后女性样本纵向回答了产后1个月、6个月和12个月时的EPDS及问卷。
产后1个月有产后抑郁（PPD；EPDS总分≥9）和自伤意念（SHI子评分≥1）的参与者，产后6个月和12个月时抑郁风险（产后6个月和12个月时的比值比[95%置信区间]分别为：20.03[16.8 - 23.8]和14.55[12.3 - 17.2]）高于产后1个月有PPD但无自伤意念的参与者（比值比分别为：8.57[7.36 - 10.0]和6.24[5.38 - 7.24]）。此外，即使产后1个月无抑郁症状的自伤意念也是产后6个月和12个月时抑郁的一个风险因素。为支持我们对产后6个月和12个月时抑郁的纵向评估，研究了这些相关因素：东日本大地震后的创伤事件或搬迁、就业状况、家庭收入、人格特质、睡眠状况、心理困扰和社会网络。结果显示，就业状况、低家庭收入和不良社会网络与产后12个月时的抑郁显著相关，但与产后6个月时的抑郁无关。
本研究表明，产后1个月有抑郁症状且伴有自伤意念的人在产后6个月和12个月时抑郁风险较高。我们的研究结果可能有助于在考虑孕期睡眠状况、心理困扰和社会网络的情况下，对产后6个月和12个月时的抑郁进行精确评估。
