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复发性病毒后横纹肌溶解症:一例报告

Recurrent Post-viral Rhabdomyolysis: A Case Report.

作者信息

Breedlove Alyssa, Rohrschneider Ashton, Virgilio Richard, Fleming John R

机构信息

Clinical, Biomedical, and Educational Research, Edward Via College of Osteopathic Medicine, Spartanburg, USA.

Clinical, Biomedical, and Educational Research, Edward Via College of Osteopathic Medicine, Auburn, USA.

出版信息

Cureus. 2024 Oct 5;16(10):e70901. doi: 10.7759/cureus.70901. eCollection 2024 Oct.

DOI:10.7759/cureus.70901
PMID:39497864
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11534438/
Abstract

Rhabdomyolysis is a relatively rare condition caused by the damage and release of myocyte contents. It occurs most commonly secondary to strenuous exercise. Rhabdomyolysis carries the risk of life-threatening negative sequelae such as acute kidney injury or death. This case report describes a middle-aged male patient who has presented with rhabdomyolysis five times over the past nine years, each following a viral illness. No inborn errors of metabolism, neuromuscular junction conditions, or myopathies were found to explain the patient's recurrent rhabdomyolysis except for two variants of unknown significance in the SYNE2 gene that has been linked with Emery-Dreifuss muscular dystrophy.

摘要

横纹肌溶解症是一种相对罕见的病症,由肌细胞内容物的损伤和释放引起。它最常见于剧烈运动之后。横纹肌溶解症存在引发诸如急性肾损伤或死亡等危及生命的负面后遗症的风险。本病例报告描述了一名中年男性患者,在过去九年中曾五次出现横纹肌溶解症,每次均在病毒感染后发生。除了与Emery-Dreifuss肌营养不良症相关的SYNE2基因中两个意义不明的变异外,未发现先天性代谢缺陷、神经肌肉接头疾病或肌病可以解释该患者反复出现的横纹肌溶解症。

相似文献

1
Recurrent Post-viral Rhabdomyolysis: A Case Report.复发性病毒后横纹肌溶解症:一例报告
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The anaesthetic management of a patient with Emery-Dreifuss muscular dystrophy.埃默里-德赖富斯肌营养不良症患者的麻醉管理
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Clin Chim Acta. 2020 Jul;506:50-54. doi: 10.1016/j.cca.2020.03.021. Epub 2020 Mar 14.
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Elevated TGF β2 serum levels in Emery-Dreifuss Muscular Dystrophy: Implications for myocyte and tenocyte differentiation and fibrogenic processes.Emery-Dreifuss 肌营养不良症患者血清 TGF β2 水平升高:对肌细胞和成纤维细胞分化及纤维生成过程的影响。
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本文引用的文献

1
Recurrent Rhabdomyolysis Induced by a Viral Illness in a Young Patient.一名年轻患者因病毒感染诱发复发性横纹肌溶解症。
Cureus. 2024 Jan 20;16(1):e52625. doi: 10.7759/cureus.52625. eCollection 2024 Jan.
2
Molecular Mechanisms of Rhabdomyolysis-Induced Kidney Injury: From Bench to Bedside.横纹肌溶解症所致肾损伤的分子机制:从实验台到临床应用
Kidney Int Rep. 2022 Sep 30;8(1):17-29. doi: 10.1016/j.ekir.2022.09.026. eCollection 2023 Jan.
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Rhabdomyolysis.横纹肌溶解症。
Dis Mon. 2020 Aug;66(8):101015. doi: 10.1016/j.disamonth.2020.101015. Epub 2020 Jun 10.
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Emery-Dreifuss muscular dystrophy.肌营养不良症伴面肩肱型。
Muscle Nerve. 2020 Apr;61(4):436-448. doi: 10.1002/mus.26782. Epub 2019 Dec 28.
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Influenza-induced rhabdomyolysis.流感诱发的横纹肌溶解症。
BMJ Case Rep. 2018 Dec 4;11(1):e226610. doi: 10.1136/bcr-2018-226610.
6
Management of Cardiac Involvement Associated With Neuromuscular Diseases: A Scientific Statement From the American Heart Association.与神经肌肉疾病相关的心脏管理:美国心脏协会的科学声明。
Circulation. 2017 Sep 26;136(13):e200-e231. doi: 10.1161/CIR.0000000000000526. Epub 2017 Aug 24.
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Rhabdomyolysis featuring muscular dystrophies.以肌肉营养不良为特征的横纹肌溶解症。
J Neurol Sci. 2016 Feb 15;361:29-33. doi: 10.1016/j.jns.2015.12.013. Epub 2015 Dec 10.
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A Systematic Review and Meta-analysis on the Epidemiology of the Muscular Dystrophies.关于肌肉萎缩症流行病学的系统评价与荟萃分析
Can J Neurol Sci. 2016 Jan;43(1):163-77. doi: 10.1017/cjn.2015.311.
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Rhabdomyolysis: a genetic perspective.横纹肌溶解症:遗传学视角
Orphanet J Rare Dis. 2015 May 2;10:51. doi: 10.1186/s13023-015-0264-3.
10
Diagnostic evaluation of rhabdomyolysis.横纹肌溶解症的诊断评估。
Muscle Nerve. 2015 Jun;51(6):793-810. doi: 10.1002/mus.24606. Epub 2015 Mar 14.