Bendary Islam M, Omar Alaa A, Goda Reham M, Ali Ahmed A, Lotfy Kareem A, Shohayeb Mohamed M
Department of Conservative Dentistry, Faculty of Dentistry, Delta University for Science and Technology, Gamasa, 11152, Dakahlia, Egypt.
Nanomedicine Research Unit, Delta University for Science and Technology, Gamasa, 11152, Dakahlia, Egypt.
BDJ Open. 2024 Nov 5;10(1):84. doi: 10.1038/s41405-024-00269-6.
This study was conducted to evaluate the antimicrobial efficacy and mechanical properties of two experimental self-disinfecting alginate preparations utilising two different antimicrobial agents; povidone-iodine and silver nanoparticles.
Alginate moulds were assigned into three groups. Additives-free control group, povidone-iodine-containing group, and silver nanoparticle-containing group. Discs from each group were obtained and assessed for their antimicrobial activities by the disc diffusion method against Staphylococcus aureus, Escherichia coli, and Candida albicans. For the elastic recovery analysis, each group was divided into 6 samples. Each sample was mixed according to its group specification and subjected to surface detail reproduction and elastic recovery according to ISO 1563:1990 specifications. All data were expressed as mean ± standard deviation for each group at the significance level of P < 0.05.
Results revealed that the experimental self-disinfection alginate possessed broad-spectrum antimicrobial activities against the tested microorganisms, compared to the control group. No statistically significant differences in elastic recovery values between all tested groups (P < 0.05) were observed. For surface detail reproduction, all samples reproduced the 50 μm line.
Povidone-iodine as well as silver nanoparticles could be used efficiently for the sanitization of alginate moulds without adverse effects on detail accuracy or elastic recovery of the impression material.
本研究旨在评估两种使用不同抗菌剂（聚维酮碘和银纳米颗粒）的实验性自消毒藻酸盐制剂的抗菌效果和机械性能。
将藻酸盐模具分为三组。无添加剂对照组、含聚维酮碘组和含银纳米颗粒组。从每组中获取圆盘，并通过纸片扩散法针对金黄色葡萄球菌、大肠杆菌和白色念珠菌评估其抗菌活性。对于弹性恢复分析，每组分为6个样本。每个样本根据其组规范进行混合，并根据ISO 1563:1990规范进行表面细节复制和弹性恢复。所有数据均表示为每组的平均值±标准差，显著性水平为P < 0.05。
结果显示，与对照组相比，实验性自消毒藻酸盐对受试微生物具有广谱抗菌活性。在所有测试组之间未观察到弹性恢复值的统计学显著差异（P < 0.05）。对于表面细节复制，所有样本均复制出了50μm的线条。
聚维酮碘以及银纳米颗粒可有效地用于藻酸盐模具的消毒，而不会对印模材料的细节准确性或弹性恢复产生不利影响。
