Shao Shu-Ming, Zhang Yi-Min, Zhang Xiao-Rui, Liu Jie, Zeng Chao-Mei, Qin Jiong
Department of Pediatrics,Peking University People's Hospital,Beijing 100044,China.
Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2024 Oct;46(5):685-691. doi: 10.3881/j.issn.1000-503X.15955.
Objective To explore the research hotspots on systemic lupus erythematosus (SLE) in pregnancy based on the bibliometric analysis of the related articles published from 2018 to 2023 and provide directions for the future research in this field. Methods PubMed,Web of Science,and Embase were searched for the articles on SLE in pregnancy that were published from January 1,2018 to December 31,2023.VOSviewer was used to visualize the high-frequency keywords in the selected articles. Results A total of 266 articles were selected,from which 25 high-frequency keywords were extracted.The bibliometric analysis showed that the available studies about SLE in pregnancy mainly focused on maternal complications,maternal and fetal outcomes,and medications.The studies were limited regarding the predictors,autoimmunity,immunotherapy,and long-term outcomes of offspring. Conclusion Maternal complications,maternal and fetal outcomes,and medications are currently hotspots in the research on SLE in pregnancy,while predictors,autoimmunity,immunotherapy,and long-term outcomes of offspring may become future research directions.
目的 通过对2018年至2023年发表的系统性红斑狼疮（SLE）妊娠相关文章进行文献计量分析，探索SLE妊娠的研究热点，并为该领域未来研究提供方向。方法 在PubMed、Web of Science和Embase数据库中检索2018年1月1日至2023年12月31日发表的SLE妊娠相关文章。使用VOSviewer对所选文章中的高频关键词进行可视化分析。结果 共筛选出266篇文章，提取出25个高频关键词。文献计量分析表明，目前关于SLE妊娠的研究主要集中在母体并发症、母胎结局和药物治疗方面。在预测因素、自身免疫、免疫治疗以及子代长期结局等方面的研究较少。结论 母体并发症、母胎结局和药物治疗是目前SLE妊娠研究的热点，而预测因素、自身免疫、免疫治疗以及子代长期结局可能成为未来的研究方向。
