Center for General Practice Medicine, Department of Rheumatology and Immunology, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, No. 158, Shangtang Road, Hangzhou, 310014, Zhejiang, China.
Zhejiang Provincial Key Laboratory of Traditional Chinese Medicine Cultivation for Arthritis Diagnosis and Treatment, Hangzhou, 310000, Zhejiang, China.
Int Urol Nephrol. 2024 Feb;56(2):781-794. doi: 10.1007/s11255-023-03715-w. Epub 2023 Aug 15.
OBJECTIVES: Lupus nephritis is a prevalent renal manifestation of systemic lupus erythematosus (SLE) and represents a significant cause of morbidity and mortality associated with the disease. This study endeavors to undertake a meticulous bibliometric analysis of LN publications to comprehend the research hotspots and future directions. METHODS: The literature on LN was acquired from the Web of Science Core Collection (WoSCC). Co-occurrence and cooperative relationship analysis of authors, institutions, countries, journals, references and keywords in the publication was performed through CiteSpace, VOSviewer and a bibliometric online analysis platform. The knowledge graphs were created, and clustering and emergence analyses were performed. RESULTS: According to the search strategy, a total of 2077 publications related to lupus nephritis (LN) have been identified, with China being the largest contributor globally. The Ohio State University emerged as the most prolific institution. Lupus is the most cited and published journal. Jan J Weening and Brad Rovin were the most prolific and cocited authors. The current research focus revolved around the "nirp3 inflammasome," "biomarker," and "voclosporin". "international society," "thrombotic microangiopathy (TMA)," and "pathway" were identified to be future research hotpots by keyword burst analysis. CONCLUSIONS: This bibliometric analysis summarizes for the first time the progress of LN research (2012-2022), and qualitatively and quantitatively evaluates the bibliometric information of LN research. There has been a steady increase in the scientific literature on LN over the past 11 years, with an average growth rate of 7.27%. In this field, researchers are primarily based in China and the United States. The pathogenic mechanisms, management strategies and prognostic outcomes of LN are acknowledged as prospective research hotspots. Bibliometrically, the research status and trends of LN publications may greatly assist and be a significant reference for future research in the area.
目的:狼疮肾炎是系统性红斑狼疮(SLE)的一种常见肾脏表现,也是导致该病发病率和死亡率升高的一个重要原因。本研究旨在对狼疮肾炎文献进行详细的计量学分析,以了解研究热点和未来方向。
方法:从 Web of Science 核心合集(WoSCC)获取狼疮肾炎相关文献。通过 CiteSpace、VOSviewer 和在线文献计量分析平台对文献中的作者、机构、国家、期刊、参考文献和关键词进行共现和合作关系分析。创建知识图谱,并进行聚类和突现分析。
结果:根据检索策略,共检索到 2077 篇与狼疮肾炎相关的文献,中国是全球最大的贡献者。俄亥俄州立大学是最具影响力的机构。《狼疮》是被引和发表文献最多的期刊。Jan J Weening 和 Brad Rovin 是最具影响力和被引最多的作者。目前的研究重点围绕“nirp3 炎症小体”、“生物标志物”和“voclosporin”展开。通过关键词突现分析,确定了“国际社会”、“血栓性微血管病(TMA)”和“通路”将成为未来的研究热点。
结论:本计量学分析首次总结了狼疮肾炎研究进展(2012-2022),并对狼疮肾炎研究的文献计量信息进行了定性和定量评价。过去 11 年,狼疮肾炎的科学文献数量稳步增加,平均增长率为 7.27%。该领域的研究人员主要来自中国和美国。狼疮肾炎的发病机制、治疗策略和预后是未来研究的潜在热点。文献计量学分析可极大地帮助和为该领域的未来研究提供重要参考。
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