中国青岛非结核分枝杆菌肺病的临床特征、菌种分布及耐药性
Clinical Characteristics, Species Distribution, and Drug Resistance of Non-Tuberculous Mycobacteria Lung Disease in Qingdao, China.
作者信息
Chu Yan, Wang Xiaomin, Dou Min, Wang Jin, Wang Baoqian, Wang Hairong, Lv Shasha, Lu Shuihua, Li Tongxia
机构信息
Qingdao Chest Hospital, Qingdao, Shandong, People's Republic of China.
National Clinical Research Center for Infectious Diseases, Shenzhen Third People's Hospital, Shenzhen, Guangdong, People's Republic of China.
出版信息
Infect Drug Resist. 2024 Nov 1;17:4807-4814. doi: 10.2147/IDR.S475015. eCollection 2024.
OBJECTIVE
To analyze the clinical characteristics, species distribution and drug resistance of patients with non-tuberculous mycobacteria (NTM) lung disease in Qingdao, China.
METHODS
Clinical data of patients with NTM lung disease and pulmonary tuberculosis (TB) treated at Qingdao Chest Hospital from July 2021 to July 2023 were retrospectively analyzed.
RESULTS
The prevalence of NTM lung disease was 8.03%, with a high rate of drug resistance during the study period. Patients with NTM lung disease had higher rates of older age, bronchiectasis, malignancy, HIV infection and bronchial dilatation shadow and lower rates of hollow shadow compared to patients with pulmonary TB.
CONCLUSION
Comprehensive understanding of NTM lung disease, improved laboratory testing techniques and appropriate treatment regimens are essential for the management of NTM lung disease.
目的
分析中国青岛非结核分枝杆菌（NTM）肺病患者的临床特征、菌种分布及耐药情况。
方法
回顾性分析2021年7月至2023年7月在青岛市胸科医院治疗的NTM肺病和肺结核患者的临床资料。
结果
NTM肺病患病率为8.03%，研究期间耐药率较高。与肺结核患者相比，NTM肺病患者年龄较大、支气管扩张、恶性肿瘤、HIV感染及支气管扩张影的发生率较高，空洞影的发生率较低。
结论
全面了解NTM肺病、改进实验室检测技术及采用合适的治疗方案对NTM肺病的管理至关重要。
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