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人工气道开放吸痰过程中基于痰液黏稠度分级的安全有效的气管内吸痰压力:一项双盲随机对照试验

Safe and effective pressure of endotracheal tube suctioning based on sputum viscosity grades during artificial airway open suctioning procedures: A double-blind randomized controlled trial.

作者信息

Liu Weiquan, Gu Chunling, Li Miqi, Xiong Jie

机构信息

Department of Intensive Care Unit, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Department of Nursing, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

出版信息

Nurs Crit Care. 2025 Jul;30(4):e13203. doi: 10.1111/nicc.13203. Epub 2024 Nov 6.

Abstract

BACKGROUND

Endotracheal tube suctioning is an effective measure to ensure airway patency during mechanical ventilation; however, inappropriate suction pressure often leads to many adverse effects.

AIM

This study aimed to investigate safe and effective suction pressures and intracatheter pressure ranges during artificial airway open suctioning procedures.

STUDY DESIGN

In this double-blind randomized controlled trial, 438 patients receiving mechanical ventilation in China were divided into nine groups according to their sputum viscosity grades and suction pressure. A random sampling method was used to select one of the three pressure groups (low-, medium- and high-pressure groups). Registered intensive care unit (ICU) nurses performed open suction manoeuvres of the artificial airway based on the pressures set by the researchers. Two teaching supervisors observed and recorded the sputum viscosity, suction pressure, minimum intracatheter pressure, maximum intracatheter pressure, heart rate, mean arterial pressure, pulse oxygen saturation, airway mucosal bleeding and sputum sound improvement score.

RESULTS

This study finally included 438 patients. The results showed that the safe and effective suction pressures were 80-120 mmHg for grade I sputum viscosity, 150 mmHg for grade II sputum viscosity and 200 mmHg for grade III sputum viscosity in open suction procedures for ICU patients. These pressure values were associated with the lowest changes in heart rate, mean arterial pressure and pulse oxygen saturation; the lowest incidence of airway mucosal bleeding; and the highest sputum sound improvement score.

CONCLUSIONS

In an open suction procedure, accurate setting of safe and effective suction pressure for sputum of different viscosity grades can not only achieve the suction effect but also have minimal impact on the vital signs and airway mucosal bleeding of patients.

RELEVANCE TO CLINICAL PRACTICE

The findings can guide critical care nurses to accurately select safe and effective initial suction pressure values rather than use general ranges when performing artificial airway open suctioning procedures.

摘要

背景

气管内吸痰是机械通气期间确保气道通畅的有效措施;然而,不当的吸引压力常常导致许多不良影响。

目的

本研究旨在探讨人工气道开放吸痰过程中的安全有效吸引压力及导管内压力范围。

研究设计

在这项双盲随机对照试验中,中国438例接受机械通气的患者根据痰液黏稠度分级和吸引压力分为9组。采用随机抽样方法从三个压力组(低、中、高压组)中选择一组。注册重症监护病房(ICU)护士根据研究人员设定的压力进行人工气道开放吸痰操作。两名教学督导员观察并记录痰液黏稠度、吸引压力、导管内最小压力、导管内最大压力、心率、平均动脉压、脉搏血氧饱和度、气道黏膜出血情况及痰液声音改善评分。

结果

本研究最终纳入438例患者。结果显示,在ICU患者开放吸痰操作中,痰液黏稠度为I级时安全有效的吸引压力为80 - 120 mmHg,II级时为150 mmHg,III级时为200 mmHg。这些压力值与心率、平均动脉压和脉搏血氧饱和度的最低变化相关;气道黏膜出血的发生率最低;痰液声音改善评分最高。

结论

在开放吸痰操作中,针对不同黏稠度等级的痰液准确设定安全有效的吸引压力,不仅能达到吸痰效果,还对患者生命体征及气道黏膜出血影响最小。

与临床实践的相关性

这些研究结果可指导重症护理护士在进行人工气道开放吸痰操作时准确选择安全有效的初始吸引压力值,而非使用一般范围。

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