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用于急性肾损伤诊断的新超声技术。

New ultrasound techniques for acute kidney injury diagnostics.

机构信息

Department of Inflammation Biology, School of Immunology and Microbial Sciences, King's College London, London.

Academic Department of Military Anaesthesia and Critical Care, Royal Centre for Defence Medicine, Birmingham, UK.

出版信息

Curr Opin Crit Care. 2024 Dec 1;30(6):571-576. doi: 10.1097/MCC.0000000000001216. Epub 2024 Sep 26.

Abstract

PURPOSE OF REVIEW

Acute kidney injury (AKI) is common in critical illness and associated with adverse outcomes. Imaging, specifically ultrasound, is increasingly finding a role in AKI diagnostics. This includes the assessment of arterial and venous blood flow, tissue perfusion and the condition of the renal parenchyma. This review provides an update on ultrasound techniques and their application to AKI in critical care.

RECENT FINDINGS

Advances have been made in arterial and venous Doppler, contrast enhanced ultrasound (CEUS) and shear wave elastography (SWE). Doppler and CEUS techniques offer benefit in terms of AKI diagnosis and in identifying patients at risk. In addition, through the demonstration of altered flow or impaired perfusion, these techniques provide information on the pathophysiology of AKI, offering potential for targeted intervention. Renal SWE, an emerging technique, assesses tissue stiffness potentially allowing exploration of the role of venous congestion in the pathogenesis of AKI.

SUMMARY

Ultrasound continues to demonstrate great promise in the diagnosis and management of AKI, offering a noninvasive means to diagnose perfusion deficits and assess response to treatments. Further research, with standardization of techniques, may allow multifaceted renal ultrasound assessment in the critically ill for more accurate diagnosis and tailored intervention in AKI.

摘要

目的综述

急性肾损伤(AKI)在危重病中很常见,与不良结局相关。影像学,特别是超声,在 AKI 的诊断中越来越发挥作用。这包括评估动脉和静脉血流、组织灌注和肾脏实质的情况。这篇综述介绍了超声技术的最新进展及其在危重病中 AKI 的应用。

最近的发现

动脉和静脉多普勒、对比增强超声(CEUS)和剪切波弹性成像(SWE)方面取得了进展。多普勒和 CEUS 技术在 AKI 的诊断和识别高危患者方面具有优势。此外,通过显示异常血流或灌注受损,这些技术提供了 AKI 病理生理学的信息,为有针对性的干预提供了可能性。作为一种新兴技术,肾脏 SWE 评估组织硬度,可能探索静脉充血在 AKI 发病机制中的作用。

总结

超声在 AKI 的诊断和管理中继续显示出巨大的潜力,提供了一种非侵入性的方法来诊断灌注不足,并评估治疗反应。进一步的研究,包括技术的标准化,可能允许对危重病患者进行多方面的肾脏超声评估,以更准确地诊断和针对 AKI 进行个体化干预。

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