Matsuo O, Kawaguchi T, Kosugi T, Mihara H
Haematologia (Budap). 1978;12(1-4):169-73.
The role of the kidney in the inactivation rate constant of UK activity (ke) was examined experimentally. The results obtained were as follows. There was a remarkable divergence in FA between the abdominal aorta and renal vein. When the bilateral renal arteries and veins were ligated, ke was 0.38, in contrast to 0.79 in the normal state. When UK was infused into rabbits with ligated renal vessels, the FA lasted for an increased period after the termination of UK infusion. These findings suggest that the kidney functions as an inactivator of UK.
通过实验研究了肾脏在尿激酶活性灭活速率常数（ke）中的作用。获得的结果如下。腹主动脉和肾静脉之间的纤维蛋白原降解产物（FDP）存在显著差异。当双侧肾动脉和静脉结扎时，ke为0.38，而正常状态下为0.79。当将尿激酶注入肾血管结扎的兔子体内时，在尿激酶输注终止后，FDP持续时间延长。这些发现表明肾脏起到了尿激酶灭活剂的作用。
