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一期单侧入路夹闭双侧大脑中动脉镜像动脉瘤的手术疗效及危险因素分析

Analysis of the Surgical Efficacy and Risk Factors of a One-stage Unilateral Approach for Clipping Bilateral MCA Mirror Aneurysms.

作者信息

Wang Chao, Yu Bing, Xu Yifan, Zhang Chonghui, Feng Yugong

机构信息

Department of Neurosurgery, The Affiliated Hospital of Qingdao University, Qingdao, China.

出版信息

J Craniofac Surg. 2025 Jun 1;36(4):1301-1305. doi: 10.1097/SCS.0000000000010830. Epub 2024 Nov 6.

DOI:10.1097/SCS.0000000000010830
PMID:39504430
Abstract

BACKGROUND

Numerous microsurgical approaches are available for treating middle cerebral artery (MCA) mirror aneurysms. However, a definitive conclusion regarding which approach yields the best outcome has yet to be reached.

METHODS

Thirty-three patients with MCA aneurysms were categorized into 2 groups: one-stage unilateral approach and other surgical approaches. Prognostic differences were compared using the Modified Rankin Scale (mRS). In addition, the length of hospital stay and costs were also compared. Among the patients with a proposed preoperative one-stage unilateral approach, they were divided into success and failure groups, and these factors were collected, including Hunt-Hess grade, contralateral aneurysm orientation and maximum diameter, contralateral A1+M1 length, and contralateral ICA bifurcation angle. These parameters were analyzed using multivariate logistic regressions to identify the risk factors.

RESULTS

The prognosis of patients in the one-stage unilateral approach group did not differ significantly from that of other surgical approaches. However, patients in the one-stage unilateral approach group experienced shorter hospital stays and incurred lower hospital expenses. In the multivariate regressions, the length of the contralateral A1+M1 was identified as an independent risk factor.

CONCLUSIONS

The one-stage unilateral pterional approach for clipping bilateral aneurysms is an effective method of treating MCA mirror aneurysms. However, in cases where patients have an excessive length of A1+M1 on the contralateral side, this approach may result in surgical failure.

摘要

背景

有多种显微手术方法可用于治疗大脑中动脉(MCA)镜像动脉瘤。然而,关于哪种方法能产生最佳结果尚未得出明确结论。

方法

33例MCA动脉瘤患者被分为两组:一期单侧入路组和其他手术入路组。使用改良Rankin量表(mRS)比较预后差异。此外,还比较了住院时间和费用。在拟行术前一期单侧入路的患者中,又分为成功组和失败组,并收集了这些因素,包括Hunt-Hess分级、对侧动脉瘤方向和最大直径、对侧A1+M1长度以及对侧颈内动脉分叉角度。使用多因素逻辑回归分析这些参数以确定危险因素。

结果

一期单侧入路组患者的预后与其他手术入路组相比无显著差异。然而,一期单侧入路组患者的住院时间较短,住院费用较低。在多因素回归分析中,对侧A1+M1的长度被确定为独立危险因素。

结论

一期单侧翼点入路夹闭双侧动脉瘤是治疗MCA镜像动脉瘤的有效方法。然而,在对侧A1+M1过长的患者中,这种方法可能导致手术失败。

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引用本文的文献

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Unilateral approach to bilateral middle cerebral artery aneurysms: a large series and a proposed grading system to predict technical difficulties.双侧大脑中动脉动脉瘤的单侧入路:一项大型研究及一种预测技术难度的分级系统建议
Neurosurg Rev. 2025 Jun 12;48(1):504. doi: 10.1007/s10143-025-03634-7.
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Single-Stage Microsurgical Clipping of Multiple Intracranial Aneurysms in a Patient with Cerebral Atherosclerosis: A Case Report and Review of Surgical Management.脑动脉粥样硬化患者多发颅内动脉瘤的单阶段显微手术夹闭:病例报告及手术治疗回顾
J Clin Med. 2025 Jan 5;14(1):269. doi: 10.3390/jcm14010269.