Department of Obstetrics and Gynecology, Nippon Medical School Hospital.
Department of Anesthesia, Higashitotsuka Memorial Hospital.
J Nippon Med Sch. 2024;91(5):426-431. doi: 10.1272/jnms.JNMS.2024_91-506.
This study assessed the effectiveness of the dural puncture epidural (DPE) technique in managing breakthrough pain in parous women receiving labor analgesia during induced labor.
This single-center retrospective cohort study included term pregnant women with singleton pregnancies who received treatment for breakthrough pain during labor. All participants underwent induced labor, and some parous women among them underwent DPE. The DPE technique consisted of placing an epidural catheter after dural puncture with a 27-gauge spinal needle. Eligible women were allocated into a DPE group and conventional epidural (CE) anesthesia group. Pain was assessed with a numerical rating scale (NRS), and a patient-controlled epidural analgesia (PCEA) bolus was administered when the NRS score was ≥3. Breakthrough pain was defined as an NRS score ≥3 during PCEA management. The primary outcome was the efficacy of rescue interventions in managing breakthrough pain, as determined by a reduction in pain intensity to an NRS score <3 before birth.
Among the 55 parous women who received labor analgesia, 44 required additional rescue administration for breakthrough pain. Of the remaining women, 23 received DPE and 19 received CE anesthesia. The DPE group experienced significantly more effective relief of breakthrough pain before birth than did the CE group (DPE: 100%; CE: 68.4%; p=0.005).
In parous women, DPE anesthesia was more effective than CE anesthesia in providing analgesia for breakthrough pain immediately before delivery during induced labor.
本研究评估了在接受诱导分娩时接受分娩镇痛的经产妇中,硬脑膜穿刺硬膜外(DPE)技术在管理突破性疼痛方面的效果。
本单中心回顾性队列研究纳入了接受分娩时突破性疼痛治疗的足月单胎妊娠孕妇。所有参与者均接受诱导分娩,其中一些经产妇接受了 DPE。DPE 技术包括在使用 27 号脊针进行硬脑膜穿刺后放置硬膜外导管。符合条件的女性被分配到 DPE 组和常规硬膜外(CE)麻醉组。疼痛采用数字评分量表(NRS)评估,当 NRS 评分≥3 时给予患者自控硬膜外镇痛(PCEA)推注。突破性疼痛定义为在 PCEA 管理期间 NRS 评分≥3。主要结局是通过减轻疼痛强度至出生前 NRS 评分<3 来评估挽救性干预措施管理突破性疼痛的效果。
在接受分娩镇痛的 55 名经产妇中,44 名需要额外的突破性疼痛抢救治疗。在其余女性中,23 名接受 DPE,19 名接受 CE 麻醉。DPE 组在分娩前缓解突破性疼痛的效果明显优于 CE 组(DPE:100%;CE:68.4%;p=0.005)。
在经产妇中,DPE 麻醉在诱导分娩期间立即分娩时提供突破性疼痛的镇痛效果优于 CE 麻醉。