Yan Yuying, Ma Ya, Xu Lidan, Lv Yuehong
Department of Reproductive Endocrinology, Women's Hospital School of Medicine Zhejiang University, Hangzhou, 310000, Zhejiang Province, People's Republic of China.
J Assist Reprod Genet. 2025 Jan;42(1):231-242. doi: 10.1007/s10815-024-03308-1. Epub 2024 Nov 6.
This study aimed to analyze the current status of women's perception of social support levels, psychological resilience, anxiety, and depression levels during IVF-ET, as well as investigate the influence of perceived social support and psychological resilience on the anxiety and depression levels of women undergoing IVF-ET and the mediating role of psychological resilience in this process.
In this study, a convenience sampling method was used to administer a questionnaire survey among 433 women undergoing IVF-ET. Then, multivariate linear regression models were applied to identify factors influencing anxiety and depression. Lastly, mediation effect analysis was conducted to explore the mediating role of psychological resilience.
The incidence of anxiety and depression was 42% and 46.4%, respectively. The mean score of the Perceived Social Support Scale (PSSS) indicated a high to moderate level of support, while the mean score of the Conner-Davidson Resilience Scale (CD-RISC) suggested moderate psychological resilience. Perceived social support was positively correlated with psychological resilience, and both were negatively correlated with anxiety and depression. Perceived social support and psychological resilience were identified as influencing factors of anxiety and depression (P < 0.001). Moreover, there was a partial mediating effect of psychological resilience between perceived social support and both anxiety and depression (P < 0.01).
These results highlight the need for healthcare providers to assess patients' levels of psychological resilience and perceived social support when developing mental health interventions in order to mitigate the risk of anxiety and depression and concomitantly enhance fertility outcomes.
本研究旨在分析体外受精-胚胎移植（IVF-ET）期间女性对社会支持水平、心理弹性、焦虑和抑郁水平的认知现状，并探讨感知社会支持和心理弹性对接受IVF-ET女性焦虑和抑郁水平的影响以及心理弹性在此过程中的中介作用。
本研究采用便利抽样法，对433名接受IVF-ET的女性进行问卷调查。然后，应用多元线性回归模型确定影响焦虑和抑郁的因素。最后，进行中介效应分析以探讨心理弹性的中介作用。
焦虑和抑郁的发生率分别为42%和46.4%。感知社会支持量表（PSSS）的平均得分表明支持水平为中高度，而康纳-戴维森心理弹性量表（CD-RISC）的平均得分表明心理弹性为中等。感知社会支持与心理弹性呈正相关，且二者均与焦虑和抑郁呈负相关。感知社会支持和心理弹性被确定为焦虑和抑郁的影响因素（P < 0.001）。此外，心理弹性在感知社会支持与焦虑和抑郁之间均存在部分中介效应（P < 0.01）。
这些结果凸显了医疗保健提供者在制定心理健康干预措施时评估患者心理弹性水平和感知社会支持的必要性，以降低焦虑和抑郁风险，并同时提高生育结局。
