Department of Sexual and Reproductive Health, National Institute for Medical Research, Mwanza Research Centre, Mwanza, Tanzania.
Department of Epidemiology and Biostatistics, Catholic University of Health and Allied Sciences, Mwanza, Tanzania.
Glob Health Action. 2024 Dec 31;17(1):2425470. doi: 10.1080/16549716.2024.2425470. Epub 2024 Nov 7.
Population data on mortality and causes of death among 5-19-year-olds are limited.
To assess levels, trends, and risk factors of cause-specific mortality and place at death among 5-19-year-olds in Tanzania (1995-2022).
Using longitudinal data from the Magu Health and Demographic Surveillance System in northwest Tanzania, we identified leading causes of death among 5-19-year-olds from verbal autopsy interviews, using physician review and a Bayesian probabilistic model (InSilicoVA). We analyzed trends in cause and place of death using three periods: 1995-2004, 2005-2014 and 2015-2022, and assessed risk factors in a Cox-proportional hazards model. We compared the results with children aged 1-4 years and global estimates for Tanzania.
Between 1995 and 2022, communicable disease mortality decreased by 73%, similar to the 76% decline among 1-4-year-olds. This decline in communicable disease mortality drove all-cause mortality declines of 43% and 48% among 5-14- and 15-19-year-olds, respectively. Non-communicable diseases and injuries gained importance, with their relative share of all deaths increasing from 15% in 1995-2004 to 58% in 2015-2022. Mortality risks were significantly higher among boys (particularly for injuries), those residing in rural areas (for non-communicable diseases), and those from the poorest households (for communicable diseases). By 2015-2022, 48% of 5-14 and 42% of 15-19-year-olds died in health facilities, up from 25% in 1995-2002.
Since 1995, the decline in communicable disease mortality drove a major all-cause mortality reduction among 5-19-year-olds. Further progress will depend on continued reduction in communicable disease mortality, particularly among the poorest, and effectively addressing non-communicable and injury mortality.
5-19 岁人群的死亡率和死因的人口数据有限。
评估坦桑尼亚 5-19 岁人群特定死因死亡率和死亡地点的水平、趋势和危险因素(1995-2022 年)。
利用坦桑尼亚西北部马古卫生和人口监测系统的纵向数据,我们通过医生审查和贝叶斯概率模型(InSilicoVA)从死因推断访谈中确定了 5-19 岁人群的主要死因。我们使用三个时期分析了死因和死亡地点的趋势:1995-2004 年、2005-2014 年和 2015-2022 年,并在 Cox 比例风险模型中评估了危险因素。我们将结果与 1-4 岁儿童和坦桑尼亚的全球估计值进行了比较。
1995 年至 2022 年间,传染病死亡率下降了 73%,与 1-4 岁儿童下降的 76%相似。传染病死亡率的下降导致 5-14 岁和 15-19 岁人群的全因死亡率分别下降了 43%和 48%。非传染性疾病和伤害的重要性增加,其在所有死亡中的相对比例从 1995-2004 年的 15%增加到 2015-2022 年的 58%。男孩(特别是伤害)、农村地区(非传染性疾病)和最贫困家庭(传染病)的死亡率风险明显更高。到 2015-2022 年,5-14 岁人群中有 48%和 15-19 岁人群中有 42%的人在医疗机构死亡,高于 1995-2002 年的 25%。
自 1995 年以来,传染病死亡率的下降导致 5-19 岁人群的全因死亡率大幅下降。进一步的进展将取决于传染病死亡率的持续下降,特别是在最贫困人群中,以及有效解决非传染性疾病和伤害死亡率问题。