Manzo-Silberman Stephane, Hawranek Michal, Banerjee Shrilla, Kaluzna-Oleksy Marta, Alasnag Mirvat, Paradies Valeria, Parapid Biljana, Sabouret Pierre, Wolczenko Agnieszka, Kunadian Vijay, Uchmanowicz Izabella, Nizard Jacky, Gilard Martine, Mehran Roxana, Chieffo Alaide
Sorbonne University, Paris, France.
Institute of Cardiology Hôpital Pitié-Salpêtrière (AP-HP), ACTION Study Group, Women as One, 75651 Paris CEDEX 13, France.
Eur Heart J Open. 2024 Oct 12;4(6):oeae087. doi: 10.1093/ehjopen/oeae087. eCollection 2024 Nov.
Cardiovascular diseases are the leading cause of death among women, and the incidence among younger women has shown the greatest increase over the last decades, in particular for acute myocardial infarction (AMI). Moreover, the prognosis of women post-AMI is poor when compared with men of similar ages. Since the 1990s, an abundant literature has highlighted the existing differences between sexes with regard to presentation, burden, and impact of traditional risk factors and of risk factors pertaining predominantly to women, the perception of risk by women and men, and the pathophysiological causations, their treatment, and prognosis. These data that have been accumulated over recent years highlight several targets for improvement. The objective of this collaborative work is to define the actions required to reverse the growing incidence of AMI in women and improve the patient pathway and care, as well as the prognosis. We aim to provide practical toolkits for different health professionals involved in the care of women, so that each step, from cardiovascular risk assessment to symptom recognition, to the AMI pathway and rehabilitation, thus facilitating that from prevention to intervention of AMI, can be optimized.
心血管疾病是女性死亡的主要原因，在过去几十年中，年轻女性的发病率增长最为显著，尤其是急性心肌梗死（AMI）。此外，与同龄男性相比，女性急性心肌梗死后的预后较差。自20世纪90年代以来，大量文献强调了在传统危险因素以及主要与女性相关的危险因素的表现、负担和影响、男性和女性对风险的认知、病理生理原因、治疗及预后方面存在的性别差异。近年来积累的这些数据突出了几个有待改善的目标。这项合作工作的目的是确定扭转女性急性心肌梗死发病率上升趋势、改善患者就医流程与护理以及预后所需采取的行动。我们旨在为参与女性护理的不同健康专业人员提供实用的工具包，以便从心血管风险评估到症状识别、再到急性心肌梗死治疗流程及康复的每一步都能得到优化，从而推动从急性心肌梗死的预防到干预的整个过程。
