Linz D H, de Garmo P L, Morton W E, Wiens A N, Coull B M, Maricle R A
J Occup Med. 1986 Feb;28(2):119-25.
Although organic solvents are essential components of an industrial economy, they are not used without risk. The relationship between excessive exposure to organic solvents and subsequent development of chronic encephalopathy has been recognized for nearly 100 years. Fifteen industrial painters who underwent evaluation in an occupational health clinic for symptoms that they related to their work were found to have a high prevalence of neurasthenic symptoms, most frequently, memory loss and personality change. Although neurologic and screening laboratory examinations showed no consistent abnormalities, psychological tests documented poor short-term memory and an array of neuropsychologic deficits. Personality profiles revealed depression, anxiety, and preoccupation with somatic concerns. These findings agree well with previous reports of "chronic painter's syndrome." Heightened awareness among industrial physicians and prospective studies to evaluate existing threshold limit values and personal protective equipment requirements are indicated.
尽管有机溶剂是工业经济的重要组成部分，但使用它们并非没有风险。过度接触有机溶剂与随后发生慢性脑病之间的关系已被认识近100年。在一家职业健康诊所接受评估的15名工业油漆工，他们因与工作相关的症状前来就诊，结果发现神经官能症症状的患病率很高，最常见的是记忆力减退和性格改变。尽管神经学和筛查实验室检查未显示出一致的异常，但心理测试记录了短期记忆力差和一系列神经心理缺陷。性格剖析显示有抑郁、焦虑以及对躯体问题的过度关注。这些发现与先前关于“慢性油漆工综合征”的报告非常吻合。工业医生需要提高认识，并开展前瞻性研究以评估现有的阈限值和个人防护装备要求。
