Min Shasha, Xu Junyan, Ren Changjie, Cai Zhonglin, Li Hongjun, Wang Zhong
Department of Urology, Gongli Hospital of Shanghai Pudong New Area, Shanghai, China.
Department of Urology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Transl Androl Urol. 2024 Oct 31;13(10):2338-2350. doi: 10.21037/tau-24-204. Epub 2024 Oct 28.
Premature ejaculation (PE) and erectile dysfunction (ED) are two common sexual symptoms of male sexual dysfunction that can strongly affect men's mental health and quality of life, and they often coexist. This aim of this study was to explore the causes and relationships between PE and ED, with a focus on the progression of PE accompanied by high-frequency ED. A deeper understanding of the causes and treatments for PE combined with ED will help improve clinical diagnosis and treatment.
We conducted a literature review of the most relevant articles related to the outlined topic in the PubMed, Google Scholar, and Web of Science databases. We did not limit language, covering both English and non-English publications, and include Chinese and English papers published between January 1996 and March 2024.
The incidence of PE and ED increases with age. Approximately one-third of patients who complain of ED suffer from PE. Similarly, in a large-scale survey in the Asia-Pacific region, more than 30% of patients with PE reported concurrent ED. Various research findings indicate a strong correlation between PE and ED. Some scholars speculate that there is a vicious cycle between PE and ED. Men who attempt to control ejaculation can reduce the level of arousal, leading to ED, whereas men who try to achieve an erection will attempt to increase the level of arousal, which can lead to PE. This cycle of mutual influence may lead to reciprocal aggravation and persistence of sexual dysfunction in both parties. Although some studies have explored the relationship between PE and ED, the specific determinants and underlying factors have not yet been clarified.
There is a close interrelationship between PE and ED, and a vicious cycle may exist between the two. This cycle of mutual influence may lead to the mutual aggravation and persistence of both sexual dysfunctions. However, the specific determining factors and potential factors underlying the correlation between the two have not been clearly identified and require further exploration.
早泄（PE）和勃起功能障碍（ED）是男性性功能障碍的两种常见症状，会严重影响男性的心理健康和生活质量，且二者常同时存在。本研究旨在探讨PE与ED之间的病因及关系，重点关注伴有高频ED的PE的进展情况。深入了解PE合并ED的病因及治疗方法将有助于改善临床诊断与治疗。
我们对PubMed、谷歌学术和科学网数据库中与上述主题最相关的文章进行了文献综述。我们不限语言，涵盖英文和非英文出版物，纳入1996年1月至2024年3月发表的中英文论文。
PE和ED的发病率随年龄增长而增加。约三分之一主诉ED的患者患有PE。同样，在亚太地区的一项大规模调查中，超过30%的PE患者报告同时患有ED。各种研究结果表明PE与ED之间存在很强的相关性。一些学者推测PE与ED之间存在恶性循环。试图控制射精的男性会降低性唤起水平，导致ED，而试图勃起的男性会试图提高性唤起水平，这可能导致PE。这种相互影响的循环可能导致双方性功能障碍相互加重并持续存在。尽管一些研究探讨了PE与ED之间的关系，但具体的决定因素和潜在因素尚未明确。
PE与ED之间存在密切的相互关系，二者之间可能存在恶性循环。这种相互影响的循环可能导致两种性功能障碍相互加重并持续存在。然而，二者相关性的具体决定因素和潜在因素尚未明确，需要进一步探索。
