Pickup J C, Viberti G C, Keen H, Parsons J A, Alberti K G
Horm Metab Res Suppl. 1979(8):202-4.
Strict control of blood glucose was achieved by continuous subcutaneous insulin infusion with a specially adapted Mill Hill Infuser for 3-4 days. This led to normalisation of some of the intermediary metabolites. In a few patients, subcutaneous infusions have been carried out for periods up to 3 months with home monitoring of blood glucose, without infection or lipodystrophy. Short-term improvement of metabolic control was associated with recovery of abnormal renal glomerular permeability to albumin.
通过使用特制的米尔山输液器进行持续皮下胰岛素输注3 - 4天,实现了血糖的严格控制。这使得一些中间代谢产物恢复正常。在少数患者中,进行了长达3个月的皮下输注,并进行血糖家庭监测,未出现感染或脂肪营养不良。代谢控制的短期改善与肾小球对白蛋白异常通透性的恢复有关。