Yum Yen Na, Poon Kean, Lau Way Kwok-Wai, Ho Fuk Chuen, Sin Kuen Fung, Chung King Man, Lee Ho Yan, Liang Di Chao
Department of Special Education and Counselling, The Education University of Hong Kong, Hong Kong, SAR, China.
School of Education, University of New South Wales, Sydney, New South Wales, Australia.
Autism Res. 2024 Dec;17(12):2702-2722. doi: 10.1002/aur.3254. Epub 2024 Nov 7.
This study aimed to evaluate the effectiveness of music therapy (MT) for children with co-occurring autism spectrum disorder (ASD) and intellectual disabilities (ID) and explore whether pre-intervention quantitative electroencephalogram (qEEG) responses can predict outcomes. A randomized controlled trial was conducted with 33 children receiving MT and 34 receiving an active control therapy. Participants received either MT or a non-musical social skills intervention for 45 min weekly over 12 weeks. Primary outcomes were measured using the Childhood Autism Rating Scale (CARS-2), along with the parent-rated Social Responsiveness Scale (SRS-2) and video coding of social behaviors. Both conditions significantly improved in CARS-2 scores at 2 weeks and 4 months post-intervention, with no differences between MT and control conditions. No changes were found in SRS-2 scores. While both conditions showed reduced disengagement after intervention, only the MT condition showed increased engagement and initiation. Strong qEEG responses to social scenes and music predicted increased initiation, indicating its potential to help tailor interventions. These results support incorporating MT into standard services and further research on qEEG predictors.
本研究旨在评估音乐疗法(MT)对同时患有自闭症谱系障碍(ASD)和智力障碍(ID)儿童的有效性,并探讨干预前定量脑电图(qEEG)反应是否能预测治疗结果。对33名接受MT治疗的儿童和34名接受积极对照治疗的儿童进行了一项随机对照试验。参与者每周接受45分钟的MT或非音乐社交技能干预,为期12周。主要结局采用儿童自闭症评定量表(CARS-2)进行测量,同时采用家长评定的社会反应量表(SRS-2)和社会行为视频编码。干预后2周和4个月时,两组的CARS-2评分均显著改善,MT组和对照组之间无差异。SRS-2评分未发现变化。虽然两组在干预后均表现出脱离接触减少,但只有MT组表现出参与度和主动性增加。对社会场景和音乐的强烈qEEG反应预测主动性增加,表明其有助于定制干预措施的潜力。这些结果支持将MT纳入标准服务,并进一步研究qEEG预测指标。