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新生儿黄疸的光疗:荧光绿和“特殊”蓝光灯的临床等效性。

Phototherapy for neonatal jaundice: clinical equivalence of fluorescent green and "special" blue lamps.

作者信息

Vecchi C, Donzelli G P, Sbrana G, Pratesi R

出版信息

J Pediatr. 1986 Mar;108(3):452-6. doi: 10.1016/s0022-3476(86)80895-2.

DOI:10.1016/s0022-3476(86)80895-2
PMID:3950827
Abstract

The relative efficacy of fluorescent green (Sylvania F20T12/G) and "special" blue (Westinghouse F20T12/BB) lamps in the phototherapy of jaundiced neonates was investigated. Two groups of low birth weight infants with a mean gestational age of 35 weeks and mean birth weight of 1930 gm, who developed hyperbilirubinemia within the first 5 days of life, were given green or blue lamp phototherapy under the same irradiation conditions. No statistically significant difference in plasma bilirubin concentrations was found between the two groups after 24 or 48 hours of treatment. Because recent measurements indicate that green lamps are much less efficient than special blue lamps for the production of Z, E isomers of bilirubin in vitro and in vivo, the clinical equivalence of these two types of lamps seems to support the hypothesis that production of structural photoisomers of bilirubin is the main mechanism of phototherapy in humans. Therefore, fluorescent green lamps provide an alternative to special blue lamps for treatment of neonatal hyperbilirubinemia.

摘要

研究了荧光绿(sylvania F20T12/G)灯和“特殊”蓝(西屋F20T12/BB)灯在新生儿黄疸光疗中的相对疗效。两组平均胎龄35周、平均出生体重1930克的低出生体重婴儿,在出生后5天内出现高胆红素血症,在相同照射条件下接受绿灯或蓝灯光疗。治疗24或48小时后,两组血浆胆红素浓度无统计学显著差异。由于最近的测量表明,绿灯在体外和体内产生胆红素Z、E异构体的效率远低于特殊蓝灯,这两种灯在临床上的等效性似乎支持了胆红素结构光异构体的产生是人类光疗主要机制的假说。因此,荧光绿灯为治疗新生儿高胆红素血症提供了特殊蓝灯的替代选择。

相似文献

1
Phototherapy for neonatal jaundice: clinical equivalence of fluorescent green and "special" blue lamps.新生儿黄疸的光疗:荧光绿和“特殊”蓝光灯的临床等效性。
J Pediatr. 1986 Mar;108(3):452-6. doi: 10.1016/s0022-3476(86)80895-2.
2
Phototherapy in the management of neonatal hyperbilirubinemia: efficacy with light sources emitting more than 500 nanometers.新生儿高胆红素血症管理中的光疗:使用发射波长超过500纳米的光源的疗效
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Efficacy of fluorescent daylight, blue, and green lamps in the management of nonhemolytic hyperbilirubinemia.荧光日光、蓝光和绿灯在非溶血性高胆红素血症治疗中的疗效。
J Pediatr. 1989 Jan;114(1):132-7. doi: 10.1016/s0022-3476(89)80620-1.
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Clinical usefulness of high intensity green light phototherapy in the treatment of neonatal jaundice.高强度绿光光疗在新生儿黄疸治疗中的临床应用价值
Eur J Pediatr. 1991 Feb;150(4):274-6. doi: 10.1007/BF01955530.
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Green light in phototherapy.光疗中的绿光
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An alternative phototherapy light combination.一种替代的光疗灯组合。
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Double phototherapy with high irradiance compared with single phototherapy in neonates with hyperbilirubinemia.高辐照度双光疗与单光疗治疗新生儿高胆红素血症的比较。
Am J Perinatol. 1995 May;12(3):178-80. doi: 10.1055/s-2007-994446.
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Early formation of bilirubin isomers during phototherapy for neonatal jaundice: effects of single vs. double fluorescent lamps vs. photodiodes.新生儿黄疸光疗期间胆红素异构体的早期形成:单荧光灯与双荧光灯及光电二极管的效果比较
Pediatr Res. 2015 Jul;78(1):56-62. doi: 10.1038/pr.2015.61. Epub 2015 Mar 20.
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Control of jaundice in preterm newborns by an inhibitor of bilirubin production: studies with tin-mesoporphyrin.胆红素生成抑制剂对早产新生儿黄疸的控制:锡-中卟啉的研究
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Direct comparison of Sn-mesoporphyrin, an inhibitor of bilirubin production, and phototherapy in controlling hyperbilirubinemia in term and near-term newborns.胆红素生成抑制剂锡-中卟啉与光疗在控制足月儿和近足月儿高胆红素血症方面的直接比较。
Pediatrics. 1995 Apr;95(4):468-74.

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Microfluidic photoreactor to treat neonatal jaundice.用于治疗新生儿黄疸的微流控光反应器。
Biomicrofluidics. 2021 Nov 24;15(6):064104. doi: 10.1063/5.0066073. eCollection 2021 Dec.
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Neonatal jaundice: phototherapy.新生儿黄疸:光疗
BMJ Clin Evid. 2015 May 22;2015:0319.
3
Neonatal jaundice.新生儿黄疸
BMJ Clin Evid. 2011 Sep 15;2011:0319.
4
Current concepts in phototherapy.
Indian J Pediatr. 1986 Sep-Oct;53(5):599-605. doi: 10.1007/BF02748663.
5
Green or blue light phototherapy for neonates with hyperbilirubinaemia.绿光或蓝光光疗用于治疗高胆红素血症新生儿。
Arch Dis Child. 1987 Aug;62(8):843-5. doi: 10.1136/adc.62.8.843.
6
Bilirubin photoconversion induced by monochromatic laser radiation. Comparison between aerobic and anaerobic experiments in vitro.单色激光辐射诱导的胆红素光转化。体外需氧与厌氧实验的比较。
Biochem J. 1988 Dec 15;256(3):841-6. doi: 10.1042/bj2560841.
7
Clinical usefulness of high intensity green light phototherapy in the treatment of neonatal jaundice.高强度绿光光疗在新生儿黄疸治疗中的临床应用价值
Eur J Pediatr. 1991 Feb;150(4):274-6. doi: 10.1007/BF01955530.