Tan K L
Department of Pediatrics, National University of Singapore.
J Pediatr. 1989 Jan;114(1):132-7. doi: 10.1016/s0022-3476(89)80620-1.
The efficacy of fluorescent daylight, green, and blue lamps in reducing bilirubin levels was compared in two groups of infants with nonhemolytic hyperbilirubinemia: healthy infants in a term nursery and infants in an intensive care unit. The decline of serum bilirubin concentration was most rapid with the blue lamps, with the duration of exposure required being significantly shorter than that with the other two types of light in both groups. The rate of decline over the first 24 hours, as well as the overall rate of decline for the whole duration of phototherapy, was also significantly greater with the blue lamps, the rate being about twice that for the green lamps in the infants in the intensive care unit; the daylight lamps were intermediate in efficacy. The daylight lamps permitted easy clinical monitoring with minimal side effects, whereas the green and blue lamps were equally disturbing to the attending personnel. The green lamps caused severe erythema and tanning in the initial 200 hours of phototherapy. It appears preferable to use either daylight lamps, which permit enhanced clinical monitoring with adequate efficacy, or special blue lamps, which provide maximal therapeutic effect, rather than green lamps, which offer neither.
在两组患有非溶血性高胆红素血症的婴儿中，比较了荧光日光灯、绿灯和蓝灯降低胆红素水平的效果：一组是足月新生儿病房中的健康婴儿，另一组是重症监护病房中的婴儿。蓝光灯使血清胆红素浓度下降最快，两组中使用蓝光灯所需的照射时间均明显短于其他两种类型的光。蓝光灯在前24小时的下降速率以及光疗整个过程中的总体下降速率也明显更大，在重症监护病房的婴儿中，其下降速率约为绿灯的两倍；日光灯的疗效居中。日光灯便于临床监测，副作用最小，而绿灯和蓝灯对医护人员同样造成干扰。绿灯在光疗最初的200小时内会导致严重的红斑和皮肤变黑。使用日光灯（可在疗效充足的情况下加强临床监测）或特殊蓝光灯（可提供最大治疗效果）似乎比绿灯更可取，因为绿灯两者皆不具备。
