Department of Cerebrovascular Diseases, Guangyuan Central Hospital, Guangyuan, China.
Department of Neurology, Chengdu Second People's Hospital, Chengdu, China.
Brain Behav. 2024 Nov;14(11):e70147. doi: 10.1002/brb3.70147.
This study investigated the association between the fetal-type posterior cerebral artery (FTP) and hypertensive thalamic hemorrhage (HTH).
Patients with hypertension who met the admission criteria between January 2020 and August 2022 were retrospectively analyzed and divided into the HTH and non-HTH groups based on the presence or absence of thalamic hemorrhage, respectively. In addition to whether the variable was an FTP, other variables with unbalanced distributions between the two groups were used as matching factors for 1:1 propensity score matching, and other variables that were not used as matching factors were used as covariates for conditional logistic regression.
A total of 722 patients were included in the study, with 115 in the HTH group and 607 in the non-HTH group. After propensity score matching, 114 patients were included in both groups. The multivariate logistic regression analysis showed that the FTP (p = 0.003, odds ratio [OR]: 2.712, 95% confidence interval [CI]: 1.407-5.225) and homocysteine levels (p = 0.007; OR: 1.051; 95% CI: 1.014-1.089) were significantly correlated with the occurrence of HTH.
The incidence of FTP is not low, and it is an independent risk factor for HTH. Early recognition and appropriate monitoring are warranted for cases of FTP.
本研究旨在探讨胎儿型大脑后动脉(FTP)与高血压性丘脑出血(HTH)之间的关系。
回顾性分析了 2020 年 1 月至 2022 年 8 月期间符合入院标准的高血压患者,根据是否存在丘脑出血将其分为 HTH 组和非 HTH 组。除了变量是否为 FTP 外,还将两组之间分布不均衡的其他变量作为 1:1 倾向评分匹配的匹配因素,其他未作为匹配因素的变量作为条件逻辑回归的协变量。
共纳入 722 例患者,HTH 组 115 例,非 HTH 组 607 例。经倾向评分匹配后,两组各纳入 114 例患者。多变量逻辑回归分析显示,FTP(p=0.003,比值比[OR]:2.712,95%置信区间[CI]:1.407-5.225)和同型半胱氨酸水平(p=0.007;OR:1.051;95% CI:1.014-1.089)与 HTH 的发生显著相关。
FTP 的发生率不低,是 HTH 的独立危险因素。对于 FTP 病例,应早期识别并进行适当监测。