McAleer J J, Murphy G J, Taylor R H, Moran J L, O'Connor F A
J R Soc Med. 1986 Feb;79(2):74-5. doi: 10.1177/014107688607900205.
Of 2947 patients admitted to a district general hospital over an 11-year period for the management of self-poisoning, 148 (5%) required intensive care unit (ICU) treatment. There was a significant increase in the number of self-poisonings admitted each year, whereas the number requiring ICU admission did not change. Therefore the proportion of patients requiring ICU admission fell significantly over the study period (P less than 0.0005). Of 898 patients admitted from 1973 to 1977, 62 (6.9%) were treated in ICU. Of 2049 patients admitted from 1978 to 1983, 86 (4.2%) required ICU treatment. It is felt that this trend is explained by a rise in parasuicidal self-poisonings. The impact of change in drug availability is evident in the significant reduction in ingestion of sedative barbiturates.
在一家地区综合医院11年间收治的2947例因自我中毒接受治疗的患者中,148例(5%)需要重症监护病房(ICU)治疗。每年收治的自我中毒患者数量显著增加,而需要入住ICU的患者数量没有变化。因此,在研究期间,需要入住ICU的患者比例显著下降(P小于0.0005)。1973年至1977年收治的898例患者中,62例(6.9%)在ICU接受治疗。1978年至1983年收治的2049例患者中,86例(4.2%)需要ICU治疗。认为这种趋势是由准自杀性自我中毒的增加所解释的。药物可获得性的变化影响明显,镇静巴比妥类药物的摄入量显著减少。