通过MH2病毒亚基因组RNA增殖产生的含Myc逆转录病毒的特性分析。
Characterization of a myc-containing retrovirus generated by propagation of an MH2 viral subgenomic RNA.
作者信息
Martin P, Henry C, Ferre F, Bechade C, Begue A, Calothy C, Debuire B, Stehelin D, Saule S
出版信息
J Virol. 1986 Mar;57(3):1191-4. doi: 10.1128/JVI.57.3.1191-1194.1986.
Abstract
We have previously isolated, from wild-type MH2 virus that contains the two oncogenes mil and myc, mutants defective in one or the other oncogene product. We report here the molecular cloning and extensive characterization of MH2 CL25 provirus lacking the v-mil oncogene. Our results indicate that this virus corresponds to the propagation of the 2.8-kilobase subgenomic RNA of MH21.
摘要
我们先前已从含有mil和myc这两个癌基因的野生型MH2病毒中分离出在一种或另一种癌基因产物上有缺陷的突变体。我们在此报告缺乏v-mil癌基因的MH2 CL25前病毒的分子克隆及广泛表征。我们的结果表明，这种病毒相当于MH21的2.8千碱基亚基因组RNA的增殖。
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