Genet Bastien, Cohen-Bittan Judith, Nicolas Michaël, Bonnet-Zamponi Dominique, Naline Charlotte, Ouafi-Hendel Dehbia, François Véronique, Cabral Christopher, Cloppet Anaïs, Davy Claire, Boddaert Jacques, Zerah Lorène
Institut Pierre Louis d'Épidémiologie et de Santé Publique (IPLESP), Equipe PEPITES, Sorbonne Université, INSERM, Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Pitié-Salpêtrière, Département de Santé Publique, Paris, France.
Département de Gériatrie, Hôpital Pitié-Salpêtrière, Assistance Publique Hôpitaux de Paris (AP-HP), Paris, France.
J Am Med Dir Assoc. 2025 Jan;26(1):105345. doi: 10.1016/j.jamda.2024.105345. Epub 2024 Nov 6.
Hip osteoarthritis and knee osteoarthritis cause significant disability and pain in older adults, often leading to hip or knee replacement surgery. Prehabilitation programs have been established for these surgeries, but there are few programs for orthogeriatrics. We evaluated the feasibility of a new multimodal prehabilitation program (MPP) for older adults before hip or knee replacement due to arthrosis: the Prehabilitation for Os (PRE4OS) study.
We conducted a multicenter feasibility study in the Greater Paris area.
Eligible adults were aged ≥75 years old awaiting hip or knee replacement with at least a 6-week delay before surgery and able to participate in the MPP follow-up. The MPP included weekly hospital sessions providing nutritional, psychological, functional, and cognitive support, along with weekly home sessions featuring physiotherapist visits.
The primary outcome was at least 80% of 1-day hospital (ODH) sessions performed by 80% of participants. Secondary outcomes included intervention achievement, quality of life, and nutritional and functional status changes. Participant's satisfaction was qualitatively assessed via structured phone interviews presurgery and at 30 days postsurgery.
From September 2021 to September 2023, a total of 27 individuals participated in the PRE4OS study. The mean (SD) age was 83 (4.3) years, with 7 males (26%) and median baseline Activities of Daily Living score 5.5 (interquartile range 5.5-6.0). Surgeries were for insertion of hip prosthesis in 17 participants (63%) and knee prosthesis in 10 (37%). The primary outcome was achieved in 89% of participants, with comparable rates for hip and knee prostheses. In total, 60% of participants rated the MPP as "excellent" presurgery and 100% at 30 days postsurgery, expressing a willingness to recommend the protocol to a friend or family.
The MPP was feasible for individuals before hip or knee replacement and was well received. Further randomized trials are needed to assess its clinical impact.
髋骨关节炎和膝骨关节炎会给老年人带来严重的残疾和疼痛,常导致髋关节或膝关节置换手术。已经为这些手术制定了术前康复计划,但针对老年骨科的项目却很少。我们评估了一种针对因关节病而需进行髋关节或膝关节置换的老年人的新型多模式术前康复计划(MPP)的可行性:骨关节炎术前康复(PRE4OS)研究。
我们在大巴黎地区进行了一项多中心可行性研究。
符合条件的成年人年龄≥75岁,正在等待髋关节或膝关节置换手术,且手术前至少有6周的延迟时间,并且能够参与MPP随访。MPP包括每周在医院进行的课程,提供营养、心理、功能和认知支持,以及每周在家中进行的课程,包括物理治疗师的家访。
主要结局是80%的参与者完成至少80%的1天住院(ODH)课程。次要结局包括干预完成情况、生活质量以及营养和功能状态的变化。通过术前和术后30天的结构化电话访谈对参与者的满意度进行定性评估。
从2021年9月到2023年9月,共有27人参与了PRE4OS研究。平均(标准差)年龄为83(4.3)岁,其中男性7人(26%),基线日常生活活动评分中位数为5.5(四分位间距5.5 - 6.0)。17名参与者(63%)进行了髋关节假体植入手术,10名(37%)进行了膝关节假体植入手术。89%的参与者实现了主要结局,髋关节和膝关节假体的比例相当。总体而言,60%的参与者在术前将MPP评为“优秀”,术后30天这一比例为100%,表示愿意向朋友或家人推荐该方案。
MPP对髋关节或膝关节置换术前的个体是可行的,并且受到好评。需要进一步的随机试验来评估其临床影响。