Smith Zacharias J, Boyer Gregory L
USDA Agricultural Research Service, Hydrology and Remote Sensing Laboratory, 10300 Baltimore Ave, Beltsville, MD, 20705, USA; State University of New York College of Environmental Science and Forestry, Department of Chemistry, 1 Forestry Dr., Syracuse, NY, 13210, USA.
USDA Agricultural Research Service, Hydrology and Remote Sensing Laboratory, 10300 Baltimore Ave, Beltsville, MD, 20705, USA.
Toxicon. 2024 Dec;252:108165. doi: 10.1016/j.toxicon.2024.108165. Epub 2024 Nov 7.
Cyanobacteria blooms were detected in 2017 and 2018 in Cayuga Lake, New York, with paralytic shellfish poisoning toxins (PSPTs) the primary toxin detected. Analysis of these samples by HPLC with chemical oxidation, receptor binding assay, ELISA, and LC-MS/MS confirmed the presence of PSPTs but each method gave highly unusual results based on the theory establishing each method. The structures of the toxins could not be identified and may be 'unusual' or unelucidated PSPTs.
2017年和2018年在纽约州卡尤加湖检测到蓝藻水华,主要检测到的毒素是麻痹性贝类中毒毒素(PSPTs)。通过化学氧化高效液相色谱法、受体结合试验、酶联免疫吸附测定和液相色谱-串联质谱法对这些样本进行分析,证实了PSPTs的存在,但基于每种方法所依据的理论,每种方法都给出了非常异常的结果。毒素的结构无法确定,可能是“异常”的或未阐明的PSPTs。