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一种伴有继发性噬血细胞性淋巴组织细胞增生症的媒介传播、空气传播和食源性感染:一例免疫功能正常患者的三重感染病例。

A vector borne, airborne and food borne infection with secondary hemophagocytic lymphohistocytosis: Case of triple infections in an immuno-competent patient.

作者信息

Kazi Abdul Nafey, Ahmed Muzeer, Wasim Muhammad Arsalan, Abbasi Lubna Iqbal, Herekar Fivzia Farooq, Patel Muhammad Junaid

机构信息

FCPS, Senior Registrar, Department of Internal Medicine, Indus Hospital and Health Network, Karachi, Pakistan.

FCPS, Senior Registrar, Department of Internal Medicine, Pak-China Hospital, Indus Hospital and Health Network, Gwadar, Pakistan.

出版信息

Indian J Med Microbiol. 2024 Nov-Dec;52:100752. doi: 10.1016/j.ijmmb.2024.100752. Epub 2024 Nov 13.

Abstract

Pakistan is endemic to several bacterial, parasitic and viral infections including tuberculosis, malaria and dengue that account for a high rate of mortality each year. These different types of infections can occur through various routes of transmission and concurrently in individuals, especially in immunocompromised but rarely among immunocompetent. We report a case of a 25 year old immunocompetent female who was admitted with an initial diagnosis of dengue fever and diagnosed as having co-infection of COVID-19 and Brucella leading to secondary hemophagocytic lymphohistiocytosis (HLH). She was managed for all three infections and complications simultaneously.

摘要

巴基斯坦是几种细菌、寄生虫和病毒感染的流行地区,包括结核病、疟疾和登革热,这些疾病每年导致很高的死亡率。这些不同类型的感染可通过多种传播途径发生,并且可在个体中同时出现,尤其是在免疫功能低下者中,但在免疫功能正常者中很少见。我们报告一例25岁免疫功能正常的女性病例,该患者最初被诊断为登革热入院,后被诊断为同时感染新冠病毒和布鲁氏菌,导致继发性噬血细胞性淋巴组织细胞增生症(HLH)。她同时接受了针对这三种感染及并发症的治疗。

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