Lan Tian, Wang Yaming
Department of Neurosurgery, Xuanwu Hospital, China International Neuroscience Institute, Capital Medical University, Beijing, China.
Department of Neurosurgery, Xuanwu Hospital, China International Neuroscience Institute, Capital Medical University, Beijing, China.
World Neurosurg. 2025 Mar;195:123351. doi: 10.1016/j.wneu.2024.10.080. Epub 2024 Nov 25.
Cryptococcoma in central nervous system is a special form of cryptococcal infection that presents as occupying lesions in human brains. Usually, it happens in cerebral or cerebellar lobes. Brainstem cryptococcoma is extremely rare, as only a few cases were reported until now. Images of brainstem cryptococcoma are usually described as multiple or single heterogeneously rim-enhancing lesions with abscess-like signs in magnetic resonance imaging. However, isolated solid lesion that was homogeneously enhanced in brainstem and without any infectious disease characters has not been reported yet. Here, we showed images of a 37-year-old male suffering from brainstem occupying lesion, which was finally diagnosed as brainstem cryptococcoma. Details of treatment strategy as well as pathologic exam were also presented. Our work highlights the varied imaging features of brainstem cryptococcoma and provides valuable information for differential diagnosis of brainstem occupying lesions.
中枢神经系统隐球菌瘤是一种特殊形式的隐球菌感染,表现为人类大脑中的占位性病变。通常,它发生在大脑或小脑叶。脑干隐球菌瘤极为罕见,截至目前仅有少数病例报道。在磁共振成像中,脑干隐球菌瘤的影像通常被描述为多个或单个边缘不均匀强化的病变,伴有脓肿样表现。然而,尚未有关于脑干孤立实性病变且均匀强化且无任何感染性疾病特征的报道。在此,我们展示了一名37岁男性患有脑干占位性病变的影像,最终被诊断为脑干隐球菌瘤。同时还介绍了治疗策略及病理检查的细节。我们的工作突出了脑干隐球菌瘤多样的影像特征,并为脑干占位性病变的鉴别诊断提供了有价值的信息。