Berstad A, Weberg R, Frøyshov Larsen I, Hoel B, Hauer-Jensen M
Scand J Gastroenterol. 1986 Jan;21(1):55-8. doi: 10.3109/00365528609034622.
A prospective study of the incidence of hiatus hernia and/or reflux oesophagitis was carried out in 670 patients referred for routine upper alimentary endoscopy. Hiatus hernia was found in 16.6% and reflux oesophagitis in 15.1% of the patients. Forty-two per cent of the patients with hernia did not have oesophagitis, whereas 63% of the patients with reflux oesophagitis had hernia. In patients without reflux oesophagitis the incidence of hiatus hernia was 8%. Reflux oesophagitis was significantly (p less than 0.001) related to hiatus hernia. The severity of the oesophagitis was significantly (p less than 0.05) related to the presence and the size of hernia, and severe oesophagitis without hernia was significantly (p less than 0.01) related to chronic alcoholism. The results suggest that a sliding hiatus hernia may play a role in the development of reflux oesophagitis.
对670例因常规上消化道内镜检查前来就诊的患者进行了一项关于食管裂孔疝和/或反流性食管炎发病率的前瞻性研究。在这些患者中，发现食管裂孔疝的比例为16.6%，反流性食管炎的比例为15.1%。42%有疝的患者没有食管炎，而63%有反流性食管炎的患者有疝。在没有反流性食管炎的患者中，食管裂孔疝的发病率为8%。反流性食管炎与食管裂孔疝显著相关（p<0.001）。食管炎的严重程度与疝的存在和大小显著相关（p<0.05），而没有疝的严重食管炎与慢性酒精中毒显著相关（p<0.01）。结果表明，滑动性食管裂孔疝可能在反流性食管炎的发生中起作用。
