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测试一种用于癫痫手术评估的在线筛查工具。

Testing an online screening tool for epilepsy surgery evaluation.

机构信息

Universidade Federal do Rio Grande do Sul, Faculdade de Medicina, Programa de Pós-Graduação em Medicina: Ciências Médicas, Porto Alegre RS, Brazil.

Hospital de Clínicas de Porto Alegre, Departamento de Neurologia, Porto Alegre RS, Brazil.

出版信息

Arq Neuropsiquiatr. 2024 Oct;82(10):1-8. doi: 10.1055/s-0044-1791659. Epub 2024 Nov 11.

Abstract

BACKGROUND

Epilepsy surgery is recognized for its effectiveness in controlling seizures in a significant number of patients with drug-resistant epilepsy. Despite this, there remains a notable deficiency in referring these patients for video-electroencephalogram (EEG) monitoring and surgical evaluation. Addressing this gap, the Canadian Appropriateness of Epilepsy Surgery (CASES), an online tool for epilepsy surgery evaluation (www.epilepsycases.com), was developed to aid physicians in the referral process of patients with refractory epilepsy to surgical assessments.

OBJECTIVE

The present study aimed to evaluate the utility of CASES in identifying candidates for epilepsy surgery, thereby facilitating clinical decision-making for patients with drug-resistant epilepsy.

METHODS

A cross-sectional analysis was conducted using the CASES platform to assess surgical candidacy among individuals with epilepsy. Participants were selected among those receiving care at the Epilepsy Clinic of the Neurology Service, Hospital de Clínicas de Porto Alegre, Brazil, over a 3-month period. The study cohort included 211 patients. Data were systematically extracted from patient medical records or collected during clinical appointments.

RESULTS

Of the evaluated cohort, 59.6% were identified as potential candidates for video-EEG monitoring and subsequent surgical evaluation. Factors significantly associated with recommendations for video-EEG and surgical assessment included seizure frequency, the number of antiseizure medications (ASMs) trialed, and the occurrence of drug-related adverse effects.

CONCLUSION

The CASES showed significant potential in guiding recommendations for video-EEG monitoring and facilitating referrals for epilepsy surgery. This tool may not only enhance patient treatments and outcomes but also contribute to cost savings in epilepsy management in both the short and long term.

摘要

背景

癫痫手术在控制耐药性癫痫患者的癫痫发作方面具有显著疗效。尽管如此,仍有相当数量的患者未能接受视频脑电图(EEG)监测和手术评估。为了解决这一差距,开发了加拿大癫痫手术适宜性(CASES)这一在线癫痫手术评估工具(www.epilepsycases.com),以帮助医生为耐药性癫痫患者的手术评估提供转诊服务。

目的

本研究旨在评估 CASES 在识别癫痫手术候选者方面的效用,从而为耐药性癫痫患者的临床决策提供便利。

方法

使用 CASES 平台对癫痫患者进行手术候选性的横断面分析。参与者选自巴西阿雷格里港临床医院神经病学服务部癫痫诊所接受治疗的患者,研究期间为 3 个月。研究队列包括 211 名患者。数据从患者病历中系统提取或在临床就诊时收集。

结果

在所评估的队列中,59.6%被确定为视频 EEG 监测和后续手术评估的潜在候选者。与视频 EEG 和手术评估建议相关的显著因素包括癫痫发作频率、试用的抗癫痫药物(ASMs)数量以及药物相关不良反应的发生。

结论

CASES 在指导视频 EEG 监测建议和促进癫痫手术转诊方面具有显著潜力。该工具不仅可以改善患者的治疗效果和预后,还可以在短期和长期内为癫痫管理节省成本。

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