Perić Aleksandar, Lazović Nikola, Sotirović Jelena, Barsova Gabriela Kopacheva, Đurđević Biserka Vukomanović
Department of Otorhinolaryngology, Faculty of Medicine of the Military Medical Academy University of Defence Belgrade Serbia.
Faculty of Medicine of the Military Medical Academy University of Defence Belgrade Serbia.
OTO Open. 2024 Nov 10;8(4):e70004. doi: 10.1002/oto2.70004. eCollection 2024 Oct-Dec.
Choanal polyps (CPs) are benign, inflammatory, solitary lesions extending toward the junction between the nasal cavity/paranasal sinus and the nasopharynx through the choana. This study aimed to evaluate the clinical and histological characteristics of CPs in children compared to adult patients. Characteristics of patients (demography, main complaints, side, localization, surgical approach, histological characteristics, accompanying chronic rhinosinusitis [CRS], association with allergic rhinitis [AR] and aspirin sensitivity, postoperative follow-up period, recurrence rates) were retrospectively reviewed. The patients were classified into children (<18 years) and adults (≥18 years). Our results suggest some clinical and histological specificities of CPs in children compared to adults. Epistaxis, oropharyngeal extension, association with AR and ipsilateral CRS, and angiomatous histological subtype of CPs are more frequent in the pediatric population. Also, the level of eosinophil infiltration of polyp tissue and recurrence rates are higher in pediatrics than in adult population.
后鼻孔息肉（CPs）是一种良性、炎性、孤立性病变，通过后鼻孔向鼻腔/鼻窦与鼻咽部的交界处延伸。本研究旨在评估儿童与成年患者相比CPs的临床和组织学特征。回顾性分析患者的特征（人口统计学、主要症状、患侧、部位、手术方式、组织学特征、伴发慢性鼻-鼻窦炎[CRS]、与变应性鼻炎[AR]的关联及阿司匹林敏感性、术后随访期、复发率）。将患者分为儿童（<18岁）和成人（≥18岁）。我们的结果提示，与成人相比，儿童CPs具有一些临床和组织学特异性。鼻出血、口咽延伸、与AR及同侧CRS的关联以及CPs的血管瘤组织学亚型在儿科人群中更为常见。此外，息肉组织中嗜酸性粒细胞浸润水平和复发率在儿科高于成人。
