[Changes in the lipid levels of the liver, plasma, aorta and cholesterol esterase activity of the rat liver during exposure to tetrachloromethane].

Content of cholesterol esters was increased 2.3-fold, triglycerides--4.7-fold, phospholipids--1.5-fold in liver tissue of CCl4-treated rats. The increase in the content of cholesterol esters and triglycerides correlated with a decrease in activity of lysosomal cholesterol esterase from liver tissue. After CCl4 intoxication content of free cholesterol was decreased 2.1-fold, free fatty acids--2-fold, phospholipids--2.3-fold, triglycerides--1.75-fold in blood. In aorta an increase in content of cholesterol esters and triglycerides was found to be 2-fold as well as activation of the cytosolic cholesterol esterase was noted. The data obtained suggest that intoxication with CCl4 affected the accumulation of cholesterol esters in the arterial wall.