Critchley Hugo D, Patchitt Joel
Department of Clinical Neuroscience, Brighton and Sussex Medical School, University of Sussex, Brighton, UK.
Curr Top Behav Neurosci. 2024 Nov 13. doi: 10.1007/7854_2024_518.
The mind is embodied, and this is relevant to mental health and psychiatric illness. Interoception is the body-to-brain axis of sensory information flow and its representation at the neural and psychological levels. Interoception is the purported basis for motivation and emotion, and as an inescapable stream of information about the health and functioning of the whole organism, it is proposed to be the foundation to the conscious unitary sense of self. Correspondingly, this central representation of internal state is relevant to understanding the expression of psychological symptoms and behaviours and ultimately psychiatric disorders. Here we review interoception, particularly from a cardiovascular perspective, and how understanding theoretical neural and psychological aspects of interoception relates to perceptions, thoughts, and feelings. We examine how perturbations in interoceptive processing are expressed in mental symptoms and psychiatric disorders and show how this knowledge may yield new treatment targets.
心智是具身的，这与心理健康和精神疾病相关。内感受是感觉信息流从身体到大脑的轴线及其在神经和心理层面的表征。内感受被认为是动机和情感的基础，并且作为关于整个有机体健康和功能的不可避免的信息流，它被认为是有意识的统一自我感的基础。相应地，这种内部状态的核心表征与理解心理症状和行为的表达以及最终的精神障碍相关。在这里，我们回顾内感受，特别是从心血管角度，以及理解内感受的理论神经和心理方面如何与感知、思想和情感相关。我们研究内感受处理中的扰动如何在精神症状和精神障碍中表现出来，并展示这些知识如何产生新的治疗靶点。
