Köhler A, Noss W, Dobberstein N, Stoltmann R, Pohl J
Z Gesamte Inn Med. 1986 Jan 1;41(1):6-9.
Out of 79 patients with metastasized carcinoma of the breast in 33% (6 patients) a response to a Tamoxifen therapy could be observed. For complete remissions the remission periods were 12.3 months, for partial remissions 9.9 months and in the group of constant findings 4.9 months. Preferably metastases of the soft parts respond to the therapy. The side effects are very insignificant. The indications for the tamoxifen therapy are represented as well as the importance of the determination of hormone receptors.
在79例转移性乳腺癌患者中，33%（6例）对他莫昔芬治疗有反应。完全缓解的缓解期为12.3个月，部分缓解为9.9个月，病情稳定组为4.9个月。软组织转移对该治疗反应较好。副作用非常轻微。文中阐述了他莫昔芬治疗的适应证以及激素受体测定的重要性。
