Hiltunen K M, Matikainen M
Acta Chir Scand. 1986 Jan;152:65-8.
Anal manometry was performed in 41 patients with chronic anal fissure in order to detect possible abnormalities of sphincter function. Comparisons were made with controls matched for sex and age. The maximal basal pressure was significantly higher in the patients with anal fissure, but no other abnormality of anal sphincter function was found in these patients. Clinical and manometric results were evaluated after 2 months in 19 patients treated with anal dilation and in 14 with lateral subcutaneous sphincterotomy. After both procedures the basal pressure was significantly reduced, but there were four failures, all after anal dilation. The study supports the view that increased pressure in the anal canal contributes in the pathophysiology of anal fissure. The condition can be managed by anal dilation or lateral subcutaneous sphincterotomy, both of which effectively reduce the basal pressure in the anal canal.
对41例慢性肛裂患者进行了肛门测压,以检测括约肌功能可能存在的异常。与年龄和性别匹配的对照组进行了比较。肛裂患者的最大基础压力明显更高,但在这些患者中未发现肛门括约肌功能的其他异常。对19例接受肛门扩张治疗的患者和14例接受外侧皮下括约肌切开术的患者在2个月后评估了临床和测压结果。两种手术后基础压力均显著降低,但有4例治疗失败,均为肛门扩张术后。该研究支持肛管压力升高在肛裂病理生理学中起作用的观点。肛裂可通过肛门扩张或外侧皮下括约肌切开术治疗,这两种方法均可有效降低肛管基础压力。